Strain background effects and genetic modifiers of hearing in mice.
about
PDZD7 is a modifier of retinal disease and a contributor to digenic Usher syndromeCorrection of the auditory phenotype in C57BL/6N mice via CRISPR/Cas9-mediated homology directed repair.Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.Identification of genetic and chemical modulators of zebrafish mechanosensory hair cell deathDevelopment of sensory, motor and behavioral deficits in the murine model of Sanfilippo syndrome type BThe R109H variant of fascin-2, a developmentally regulated actin crosslinker in hair-cell stereocilia, underlies early-onset hearing loss of DBA/2J micePopulation genomics of wild and laboratory zebrafish (Danio rerio)Espins and the actin cytoskeleton of hair cell stereocilia and sensory cell microvilli.A short splice form of Xin-actin binding repeat containing 2 (XIRP2) lacking the Xin repeats is required for maintenance of stereocilia morphology and hearing functionAge-related changes in auditory nerve-inner hair cell connections, hair cell numbers, auditory brain stem response and gap detection in UM-HET4 mice.Vestibular dysfunction, altered macular structure and trait localization in A/J inbred mice.FVB/NJ mice demonstrate a youthful sensitivity to noise-induced hearing loss and provide a useful genetic model for the study of neural hearing lossPathophysiology of age-related hearing loss (peripheral and central).Digenic inheritance of deafness caused by 8J allele of myosin-VIIA and mutations in other Usher I genesA new mouse mutant of the Cdh23 gene with early-onset hearing loss facilitates evaluation of otoprotection drugs.Polygenic inheritance of sensorineural hearing loss (Snhl2, -3, and -4) and organ of Corti patterning defect in the ALR/LtJ mouse strainRoles of the espin actin-bundling proteins in the morphogenesis and stabilization of hair cell stereocilia revealed in CBA/CaJ congenic jerker mice.Modifiers of hearing impairment in humans and mice.Interactions of hearing loss and diabetes mellitus in the middle age CBA/CaJ mouse model of presbycusis.Neurobehavioral abnormalities in the dysbindin-1 mutant, sandy, on a C57BL/6J genetic background.Hearing loss in a mouse model of Muenke syndromeA locus on distal chromosome 10 (ahl4) affecting age-related hearing loss in A/J mice.Genetic dependence of cochlear cells and structures injured by noise.Production of germline transgenic prairie voles (Microtus ochrogaster) using lentiviral vectorsMutations in CLDN14 are associated with different hearing thresholds.Discovery Genetics - The History and Future of Spontaneous Mutation Research.Longitudinal fundus and retinal studies with SD-OCT: a comparison of five mouse inbred strains.Validation of simple sequence length polymorphism regions of commonly used mouse strains for marker assisted speed congenics screening.Association of a citrate synthase missense mutation with age-related hearing loss in A/J miceA QTL on Chr 5 modifies hearing loss associated with the fascin-2 variant of DBA/2J miceMutation profile of the CDH23 gene in 56 probands with Usher syndrome type I.Wild-derived mouse stocks: an underappreciated tool for aging research.Sirt1 deficiency protects cochlear cells and delays the early onset of age-related hearing loss in C57BL/6 mice.A new Atp2b2 deafwaddler allele, dfw(i5), interacts strongly with Cdh23 and other auditory modifiers.Hearing impairment in hypothyroid dwarf mice caused by mutations of the thyroid peroxidase geneDoes age matter? The impact of rodent age on study outcomesNew treatment options for hearing loss.Vesicular glutamate transporter 3 in age-dependent optic neuropathyReduced spiral ganglion neuronal loss by adjunctive neurotrophin-3 in experimental pneumococcal meningitis.Genetic rodent models of brain disorders: Perspectives on experimental approaches and therapeutic strategies.
P2860
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P2860
Strain background effects and genetic modifiers of hearing in mice.
description
2006 nî lūn-bûn
@nan
2006 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մարտին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Strain background effects and genetic modifiers of hearing in mice.
@ast
Strain background effects and genetic modifiers of hearing in mice.
@en
type
label
Strain background effects and genetic modifiers of hearing in mice.
@ast
Strain background effects and genetic modifiers of hearing in mice.
@en
prefLabel
Strain background effects and genetic modifiers of hearing in mice.
@ast
Strain background effects and genetic modifiers of hearing in mice.
@en
P2093
P2860
P1433
P1476
Strain background effects and genetic modifiers of hearing in mice.
@en
P2093
Kenneth R Johnson
Konrad Noben-Trauth
Qing Yin Zheng
P2860
P356
10.1016/J.BRAINRES.2006.02.021
P407
P577
2006-03-31T00:00:00Z