An improved open-channel structure of MscL determined from FRET confocal microscopy and simulation
about
Mechanosensitive channels: what can they do and how do they do it?The role of MscL amphipathic N terminus indicates a blueprint for bilayer-mediated gating of mechanosensitive channelsDihydrostreptomycin Directly Binds to, Modulates, and Passes through the MscL Channel PoreForce transduction and lipid binding in MscL: a continuum-molecular approachBreaking the hydrophobicity of the MscL pore: insights into a charge-induced gating mechanismA decade and a half of protein intrinsic disorder: biology still waits for physicsModeling and simulation of ion channels.Controlled delivery of bioactive molecules into live cells using the bacterial mechanosensitive channel MscL.Structural investigation of MscL gating using experimental data and coarse grained MD simulationsConditionally and transiently disordered proteins: awakening cryptic disorder to regulate protein function.Binding of fullerenes and nanotubes to MscL.Bacterial mechanosensitive channels as a paradigm for mechanosensory transduction.The activation mode of the mechanosensitive ion channel, MscL, by lysophosphatidylcholine differs from tension-induced gatingBilayer-mediated clustering and functional interaction of MscL channels.Global structural changes of an ion channel during its gating are followed by ion mobility mass spectrometryA new antibiotic with potent activity targets MscL.Scanning MscL Channels with Targeted Post-Translational Modifications for Functional Alterations.The Combined Effect of Hydrophobic Mismatch and Bilayer Local Bending on the Regulation of Mechanosensitive Ion Channels.Hydrophobic gating of mechanosensitive channel of large conductance evidenced by single-subunit resolution.The MscS and MscL families of mechanosensitive channels act as microbial emergency release valves.The dynamics of protein-protein interactions between domains of MscL at the cytoplasmic-lipid interfaceFRET spectrometry: a new tool for the determination of protein quaternary structure in living cells.Single molecule FRET reveals pore size and opening mechanism of a mechano-sensitive ion channel.Disorder in the lifetime of a proteinMagnetic nanoparticles for "smart liposomes".GsMTx4: Mechanism of Inhibiting Mechanosensitive Ion Channels.Nanomechanical properties of MscL α helices: A steered molecular dynamics studyMolecular dynamics study on protein-water interplay in the mechanogating of the bacterial mechanosensitive channel MscL.Functional similarities between heterogeneously and homogenously expressed MscL constructs.A cytoplasmic helix is required for pentamer formation of the Escherichia coli MscL mechanosensitive channel.Pulling MscL open via N-terminal and TM1 helices: A computational study towards engineering an MscL nanovalve.Flying-patch patch-clamp study of G22E-MscL mutant under high hydrostatic pressureThe effect of local bending on gating of MscL using a representative volume element and finite element simulation.Do bifunctional labels solve the problem of dye diffusion in FRET analysis?Structural Dynamics of the MscL C-terminal Domain.Structure-based membrane dome mechanism for Piezo mechanosensitivity.Gating mechanism of mechanosensitive channel of large conductance: a coupled continuum mechanical-continuum solvation approach.Engineering a pH-Sensitive Liposomal MRI Agent by Modification of a Bacterial Channel.Inducible release of particulates from liposomes using the mechanosensitive channel of large conductance and L-α-lysophosphatidylcholine.The voltage-dependence of MscL has dipolar and dielectric contributions and is governed by local intramembrane electric field
P2860
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P2860
An improved open-channel structure of MscL determined from FRET confocal microscopy and simulation
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
An improved open-channel struc ...... ocal microscopy and simulation
@ast
An improved open-channel struc ...... ocal microscopy and simulation
@en
An improved open-channel struc ...... ocal microscopy and simulation
@nl
type
label
An improved open-channel struc ...... ocal microscopy and simulation
@ast
An improved open-channel struc ...... ocal microscopy and simulation
@en
An improved open-channel struc ...... ocal microscopy and simulation
@nl
prefLabel
An improved open-channel struc ...... ocal microscopy and simulation
@ast
An improved open-channel struc ...... ocal microscopy and simulation
@en
An improved open-channel struc ...... ocal microscopy and simulation
@nl
P2093
P2860
P356
P1476
An improved open-channel struc ...... ocal microscopy and simulation
@en
P2093
Annette C Hurst
Boris Martinac
Paul Rigby
Prithwish Pal
Takeshi Nomura
P2860
P304
P356
10.1085/JGP.200910376
P577
2010-10-01T00:00:00Z