The role of post-translational modifications in fine-tuning BLM helicase function during DNA repair
about
Functions of Ubiquitin and SUMO in DNA Replication and Replication StressDisruption of SUMO-targeted ubiquitin ligases Slx5-Slx8/RNF4 alters RecQ-like helicase Sgs1/BLM localization in yeast and human cells.A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation.Regulation of BLM Nucleolar LocalizationProtein degradation pathways regulate the functions of helicases in the DNA damage response and maintenance of genomic stabilityhSSB1 associates with and promotes stability of the BLM helicaseTargeting SOD1 induces synthetic lethal killing in BLM- and CHEK2-deficient colorectal cancer cells.Lysine Acetylation and Succinylation in HeLa Cells and their Essential Roles in Response to UV-induced Stress.Single-molecule sorting of DNA helicases.Bloom's syndrome: Why not premature aging?: A comparison of the BLM and WRN helicases.Mitotic phosphorylation of Bloom helicase at Thr182 is required for its proteasomal degradation and maintenance of chromosomal stability.Smc5/6 complex regulates Sgs1 recombination functions.Crosstalk between the nucleolus and the DNA damage response.RecQ helicase BLM regulates prostate cancer cell proliferation and apoptosis.Sgs1's roles in DNA end resection, HJ dissolution, and crossover suppression require a two-step SUMO regulation dependent on Smc5/6.RECQ-like helicases Sgs1 and BLM regulate R-loop-associated genome instability.Mouse embryonic stem cells have increased capacity for replication fork restart driven by the specific Filia-Floped protein complex.A tri-serine cluster within the topoisomerase IIα-interaction domain of the BLM helicase is required for regulating chromosome breakage in human cells.Purification and enzymatic characterization of Gallus gallus BLM helicase.MRN complex-dependent recruitment of ubiquitylated BLM helicase to DSBs negatively regulates DNA repair pathways.
P2860
Q26744570-11BB3E6A-EC44-4AFB-B9BE-B9D6F4796A59Q27937985-5C79B07E-9F57-49BB-9E6B-B50DC468E8DEQ31814841-16DC32E4-D19C-4DDC-802D-1DAB27FECEB0Q34047411-FBBE76CC-A839-4768-82D7-33CF8EAE6651Q35833998-EBBBF1D3-1AC4-4EB7-8719-4B850949FD3BQ36372465-2D473A1E-A849-41F1-BDB3-2460055FF684Q36413938-9F25022D-A7E8-4509-BDD8-94B91D48189CQ37121826-C92793FD-DD35-460A-BF0F-0AF06DB93402Q38292340-B2E1E01A-2EB8-44FC-A0FD-5E6C2BA8FA25Q38847700-51B8200C-8914-46F4-BBB2-6E8CB86AE257Q38869143-E46E3C94-9FDA-4E48-A81F-52F8860A0AB6Q38963402-BBBA4B4B-CDF2-4BCB-A374-18A6D0E33335Q39098597-000F54F7-8F15-4842-A00A-E87E29449EC6Q41701816-03804C0C-82CF-4A71-B24B-69B3B9C9C091Q42203705-916F5A40-C244-4FB8-A468-40948465482FQ46282367-CEF3FF37-ABDD-4660-BE2A-4642309C4F0CQ47417363-2593233D-8852-4ABA-B022-C2B554ABA8A0Q49552769-9641AD92-7392-4F76-8D1E-483A008F415DQ51088270-C5CEB601-6411-464D-9249-BC5CD2196BC2Q52361058-92FE7B4B-DD2D-4A08-A2CF-B8B51A0B80D3
P2860
The role of post-translational modifications in fine-tuning BLM helicase function during DNA repair
description
2014 nî lūn-bûn
@nan
2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
The role of post-translational ...... ase function during DNA repair
@ast
The role of post-translational ...... ase function during DNA repair
@en
The role of post-translational ...... ase function during DNA repair
@nl
type
label
The role of post-translational ...... ase function during DNA repair
@ast
The role of post-translational ...... ase function during DNA repair
@en
The role of post-translational ...... ase function during DNA repair
@nl
prefLabel
The role of post-translational ...... ase function during DNA repair
@ast
The role of post-translational ...... ase function during DNA repair
@en
The role of post-translational ...... ase function during DNA repair
@nl
P2860
P1433
P1476
The role of post-translational ...... ase function during DNA repair
@en
P2093
Stefanie Böhm
P2860
P304
P356
10.1016/J.DNAREP.2014.07.007
P577
2014-08-24T00:00:00Z