Itraconazole suppresses the growth of glioblastoma through induction of autophagy: involvement of abnormal cholesterol trafficking. - sprookjes - yvandenbroek - TriplyDB

Itraconazole suppresses the growth of glioblastoma through induction of autophagy: involvement of abnormal cholesterol trafficking.

Itraconazole suppresses the growth of glioblastoma through induction of autophagy: involvement of abnormal cholesterol trafficking.

http://www.wikidata.org/entity/Q34373100

about

Glioblastoma, hypoxia and autophagy: a survival-prone 'ménage-à-trois'CUSP9* treatment protocol for recurrent glioblastoma: aprepitant, artesunate, auranofin, captopril, celecoxib, disulfiram, itraconazole, ritonavir, sertraline augmenting continuous low dose temozolomide.Repurposing Drugs in Oncology (ReDO)-itraconazole as an anti-cancer agent.Elaiophylin, a novel autophagy inhibitor, exerts antitumor activity as a single agent in ovarian cancer cells Therapeutic and prophylactic activity of itraconazole against human rhinovirus infection in a murine model.PRKAA/AMPK restricts HBV replication through promotion of autophagic degradation.Itraconazole induces apoptosis and cell cycle arrest via inhibiting Hedgehog signaling in gastric cancer cells.Individualized network-based drug repositioning infrastructure for precision oncology in the panomics era.Repurposing itraconazole as an anticancer agent.Hydrogel Environment Supports Cell Culture Expansion of a Grade IV Astrocytoma.Upregulation of CYP17A1 by Sp1-mediated DNA demethylation confers temozolomide resistance through DHEA-mediated protection in glioma.Toxicarioside O induces protective autophagy in a sirtuin-1-dependent manner in colorectal cancer cells.Rapamycin promotes differentiation increasing βIII-tubulin, NeuN, and NeuroD while suppressing nestin expression in glioblastoma cells Bitter melon extract inhibits breast cancer growth in preclinical model by inducing autophagic cell death.A novel multikinase inhibitor R8 exhibits potent inhibition on cancer cells through both apoptosis and autophagic cell death.Econazole nitrate inhibits PI3K activity and promotes apoptosis in lung cancer cells.Antitumor effects of the antiparasitic agent ivermectin via inhibition of Yes-associated protein 1 expression in gastric cancer.mTOR-Dependent Cell Proliferation in the Brain.VDAC1 is a molecular target in glioblastoma, with its depletion leading to reprogrammed metabolism and reversed oncogenic properties.Itraconazole attenuates hepatic gluconeogenesis and promotes glucose uptake by regulating AMPK pathway.Prucalopride inhibits the glioma cells proliferation and induces autophagy via AKT-mTOR pathway.Itraconazole targets cell cycle heterogeneity in colorectal cancer.Tubeimoside I induces accumulation of impaired autophagolysosome against cervical cancer cells by both initiating autophagy and inhibiting lysosomal function Hedgehog Signaling Pathway and Autophagy in Cancer

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P2860

Itraconazole suppresses the growth of glioblastoma through induction of autophagy: involvement of abnormal cholesterol trafficking.

http://www.wikidata.org/entity/Q34373100

description

2014 nî lūn-bûn

@nan

2014 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2014 թվականի մայիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Itraconazole suppresses the gr ...... ormal cholesterol trafficking.

@ast

Itraconazole suppresses the gr ...... ormal cholesterol trafficking.

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Itraconazole suppresses the gr ...... ormal cholesterol trafficking.

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type

label

Itraconazole suppresses the gr ...... ormal cholesterol trafficking.

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Itraconazole suppresses the gr ...... ormal cholesterol trafficking.

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Itraconazole suppresses the gr ...... ormal cholesterol trafficking.

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prefLabel

Itraconazole suppresses the gr ...... ormal cholesterol trafficking.

@ast

Itraconazole suppresses the gr ...... ormal cholesterol trafficking.

@en

Itraconazole suppresses the gr ...... ormal cholesterol trafficking.

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Itraconazole suppresses the gr ...... ormal cholesterol trafficking.

@en

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Canhua Huang

http://www.w3.org/2001/XMLSchema#string

Edouard C Nice

http://www.w3.org/2001/XMLSchema#string

Jiang Lan

http://www.w3.org/2001/XMLSchema#string

Jingyi Li

http://www.w3.org/2001/XMLSchema#string

Kefei Yuan

http://www.w3.org/2001/XMLSchema#string

Kui Wang

http://www.w3.org/2001/XMLSchema#string

Lin Cheng

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Linzhi Zou

http://www.w3.org/2001/XMLSchema#string

Na Xie

http://www.w3.org/2001/XMLSchema#string

Rong Xiang

http://www.w3.org/2001/XMLSchema#string

P2860

Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation

Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13

Intracellular cholesterol transport

Cholesterol trafficking is required for mTOR activation in endothelial cells

Itraconazole inhibits angiogenesis and tumor growth in non-small cell lung cancer

mTOR: from growth signal integration to cancer, diabetes and ageing

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery

Regulation of autophagy by cytoplasmic p53

TOR, a central controller of cell growth.

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1241-1255

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10.4161/AUTO.28912

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7

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10

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