Increased noncanonical splicing of autoantigen transcripts provides the structural basis for expression of untolerized epitopes
about
The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetesMECHANISMS IN ENDOCRINOLOGY: Alternative splicing: the new frontier in diabetes researchBreaking tolerance to thyroid antigens: changing concepts in thyroid autoimmunityAn unconventional antigen translated by a novel internal ribosome entry site elicits antitumor humoral immune reactionsIdentification of a novel function of CX-4945 as a splicing regulatorNovel tumor antigens elicit anti-tumor humoral immune reactions in a subset of patients with polycythemia veraA novel unconventional antigen MPD5 elicits anti-tumor humoral immune responses in a subset of patients with polycythemia veraA high-throughput screening strategy identifies cardiotonic steroids as alternative splicing modulatorsInflammasomes are differentially expressed in cardiovascular and other tissues.Inflammatory and autoimmune reactions in atherosclerosis and vaccine design informatics.Cryptic splice sites and split genes.Immunogenicity of autoantigens.Evolutionary dynamics of human autoimmune disease genes and malfunctioned immunological genes.Nova1 is a master regulator of alternative splicing in pancreatic beta cells.Alternative splicing in multiple sclerosis and other autoimmune diseases.Structural evidence of anti-atherogenic microRNAsAlternative splicing factor ASF/SF2 is down regulated in inflamed muscle.MicroRNAs and other mechanisms regulate interleukin-17 cytokines and receptors.An array of possibilities for the study of autoimmunity.Analysis for Carom complex, signaling and function by database mining.Immunogenetics of pemphigus: an update.Bioinformatics for study of autoimmunity.Identification of novel pretranslational regulatory mechanisms for NF-κB activation.VASCULAR INFLAMMATION AND ATHEROGENESIS ARE ACTIVATED VIA RECEPTORS FOR PAMPs AND SUPPRESSED BY REGULATORY T CELLS.Availability of autoantigenic epitopes controls phenotype, severity, and penetrance in TCR Tg autoimmune gastritisThe Role of Immunogenicity in Cardiovascular Disease."Omics" Technologies and the Immune System (a) , (b).The Characterization of GSDMB Splicing and Backsplicing Profiles Identifies Novel Isoforms and a Circular RNA That Are Dysregulated in Multiple Sclerosis.Self-antigen expression in the peripheral immune system: roles in self-tolerance and type 1 diabetes pathogenesis.Processing sites are different in the generation of HLA-A2.1-restricted, T cell reactive tumor antigen epitopes and viral epitopes.Alternative splicing: the pledge, the turn, and the prestige : The key role of alternative splicing in human biological systems.Lysophospholipid Receptors, as Novel Conditional Danger Receptors and Homeostatic Receptors Modulate Inflammation-Novel Paradigm and Therapeutic PotentialExploring the interplay between autoimmunity and cancer to find the target therapeutic hotspots.Global Gene Expression Profiling and Alternative Splicing Events during the Chondrogenic Differentiation of Human Cartilage Endplate-Derived Stem Cells.Cytokine-induced dicing and splicing in the beta-cell and the immune response in type 1 diabetes.Promiscuous mRNA splicing under the control of AIRE in medullary thymic epithelial cells.Low-Intensity Ultrasound-Induced Anti-inflammatory Effects Are Mediated by Several New Mechanisms Including Gene Induction, Immunosuppressor Cell Promotion, and Enhancement of Exosome Biogenesis and Docking.Transcription-Associated Mutation Promotes RNA Complexity in Highly Expressed Genes-A Major New Source of Selectable Variation.GATA3, HDAC6, and BCL6 Regulate FOXP3+ Treg Plasticity and Determine Treg Conversion into Either Novel Antigen-Presenting Cell-Like Treg or Th1-Treg.Increased RNA Editing May Provide a Source for Autoantigens in Systemic Lupus Erythematosus.
P2860
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P2860
Increased noncanonical splicing of autoantigen transcripts provides the structural basis for expression of untolerized epitopes
description
2004 nî lūn-bûn
@nan
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Increased noncanonical splicin ...... ession of untolerized epitopes
@ast
Increased noncanonical splicin ...... ession of untolerized epitopes
@en
Increased noncanonical splicin ...... ession of untolerized epitopes
@nl
type
label
Increased noncanonical splicin ...... ession of untolerized epitopes
@ast
Increased noncanonical splicin ...... ession of untolerized epitopes
@en
Increased noncanonical splicin ...... ession of untolerized epitopes
@nl
prefLabel
Increased noncanonical splicin ...... ession of untolerized epitopes
@ast
Increased noncanonical splicin ...... ession of untolerized epitopes
@en
Increased noncanonical splicin ...... ession of untolerized epitopes
@nl
P2093
P2860
P1476
Increased noncanonical splicin ...... ession of untolerized epitopes
@en
P2093
David P Huston
Xiao-Feng Yang
Zeyu Xiong
P2860
P304
P356
10.1016/J.JACI.2004.09.006
P407
P577
2004-12-01T00:00:00Z