5-Azacytidine can induce lethal mutagenesis in human immunodeficiency virus type 1. - sprookjes - yvandenbroek - TriplyDB

5-Azacytidine can induce lethal mutagenesis in human immunodeficiency virus type 1.

5-Azacytidine can induce lethal mutagenesis in human immunodeficiency virus type 1.

http://www.wikidata.org/entity/Q35000909

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Extinction of hepatitis C virus by ribavirin in hepatoma cells involves lethal mutagenesis Viral mutation rates Current perspectives on HIV-1 antiretroviral drug resistance Viral quasispecies evolution Mutation of HIV-1 genomes in a clinical population treated with the mutagenic nucleoside KP1461 Stochastic simulations suggest that HIV-1 survives close to its error threshold A screen of approved drugs and molecular probes identifies therapeutics with anti-Ebola virus activity.Exploiting drug repositioning for discovery of a novel HIV combination therapy Antiretroviral activity of 5-azacytidine during treatment of a HTLV-1 positive myelodysplastic syndrome with autoimmune manifestations.Activity of a novel combined antiretroviral therapy of gemcitabine and decitabine in a mouse model for HIV-1.Retroviral vectors for analysis of viral mutagenesis and recombination.Evaluation of anti-HIV-1 mutagenic nucleoside analogues.Effects of ribavirin on the replication and genetic stability of porcine reproductive and respiratory syndrome virus A general method to eliminate laboratory induced recombinants during massive, parallel sequencing of cDNA library.Lethal mutagenesis: targeting the mutator phenotype in cancer.HIV-1 and HIV-2 exhibit similar mutation frequencies and spectra in the absence of G-to-A hypermutation.Lack of mutational hot spots during decitabine-mediated HIV-1 mutagenesis HIV-1 transcription and latency: an update.Host SAMHD1 protein promotes HIV-1 recombination in macrophages.Discovery of novel ribonucleoside analogs with activity against human immunodeficiency virus type 1 Mutation rates and intrinsic fidelity of retroviral reverse transcriptases.Arenaviruses and lethal mutagenesis. Prospects for new ribavirin-based interventions."Old Dogs with New Tricks": exploiting alternative mechanisms of action and new drug design strategies for clinically validated HIV targets.Expression of chimeric receptor CD4ζ by natural killer cells derived from human pluripotent stem cells improves in vitro activity but does not enhance suppression of HIV infection in vivo.Anti-HIV-1 activity of Trim 37.Rapid Determination of HIV-1 Mutant Frequencies and Mutation Spectra Using an mCherry/EGFP Dual-Reporter Viral Vector.Effective lethal mutagenesis of influenza virus by three nucleoside analogs.Novel inhibitors of human immunodeficiency virus type 2 infectivity.5,6-Dihydro-5-aza-2'-deoxycytidine potentiates the anti-HIV-1 activity of ribonucleotide reductase inhibitors.Concomitant lethal mutagenesis of human immunodeficiency virus type 1.Back to the future: revisiting HIV-1 lethal mutagenesis.5-Azacytidine Enhances the Mutagenesis of HIV-1 by Reduction to 5-Aza-2'-Deoxycytidine.Triterpene derivatives that inhibit human immunodeficiency virus type 1 replication.Repurposing of nucleoside- and nucleobase-derivative drugs as antibiotics and biofilm inhibitors.The external domains of the HIV-1 envelope are a mutational cold spot.Characterization of permeability, stability and anti-HIV-1 activity of decitabine and gemcitabine divalerate prodrugs.Favipiravir elicits antiviral mutagenesis during virus replication in vivo.Interrelationship between HIV-1 fitness and mutation rate.Changes in protein domains outside the catalytic site of the bacteriophage Qβ replicase reduce the mutagenic effect of 5-azacytidine.Error catastrophe and phase transition in the empirical fitness landscape of HIV.

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P2860

5-Azacytidine can induce lethal mutagenesis in human immunodeficiency virus type 1.

http://www.wikidata.org/entity/Q35000909

description

2009 nî lūn-bûn

@nan

2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

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2009年論文

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2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

5-Azacytidine can induce lethal mutagenesis in human immunodeficiency virus type 1.

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5-Azacytidine can induce lethal mutagenesis in human immunodeficiency virus type 1.

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type

label

5-Azacytidine can induce lethal mutagenesis in human immunodeficiency virus type 1.

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5-Azacytidine can induce lethal mutagenesis in human immunodeficiency virus type 1.

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prefLabel

5-Azacytidine can induce lethal mutagenesis in human immunodeficiency virus type 1.

@ast

5-Azacytidine can induce lethal mutagenesis in human immunodeficiency virus type 1.

@en

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P1433

Journal of Virology

P1476

5-Azacytidine can induce lethal mutagenesis in human immunodeficiency virus type 1

@en

P2093

Christine L Clouser

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Louis M Mansky

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Steven Patterson

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P2860

RNA virus error catastrophe: direct molecular test by using ribavirin

Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity

Response of foot-and-mouth disease virus to increased mutagenesis: influence of viral load and fitness in loss of infectivity

Ribavirin Reveals a Lethal Threshold of Allowable Mutation Frequency for Hantaan Virus

5-Azacytidine and RNA secondary structure increase the retrovirus mutation rate

Effect of Ribavirin on the Mutation Rate and Spectrum of Hepatitis C Virus In Vivo

Kinetic studies with 5-azacytidine-5'-triphosphate and DNA-dependent RNA polymerase

5-azacytidine and 5-azadeoxycytidine inhibit human immunodeficiency virus type 1 replication in vitro

Lethal mutagenesis of HIV with mutagenic nucleoside analogs

The antiretrovirus drug 3'-azido-3'-deoxythymidine increases the retrovirus mutation rate

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11950-11958

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scholarly article

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10.1128/JVI.01406-09

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22

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83

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2009-09-02T00:00:00Z

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19726509

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2772699

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