Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1.
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The MHC locus and genetic susceptibility to autoimmune and infectious diseases.A Genome-Wide SNP Linkage Analysis Suggests a Susceptibility Locus on 6p21 for Ankylosing Spondylitis and Inflammatory Back Pain Trait.Comparison of HLA allelic imputation programs.Structural Basis for Antigenic Peptide Recognition and Processing by Endoplasmic Reticulum (ER) Aminopeptidase 2An HLA-C amino-acid variant in addition to HLA-B*27 confers risk for ankylosing spondylitis in the Korean population.Contribution of a Non-classical HLA Gene, HLA-DOA, to the Risk of Rheumatoid Arthritis.Review: Enthesitis: New Insights Into Pathogenesis, Diagnostic Modalities, and Treatment.ERAP1 association with ankylosing spondylitis is attributable to common genotypes rather than rare haplotype combinations.The Human Leukocyte Antigen (HLA)-B27 Peptidome in Vivo, in Spondyloarthritis-susceptible HLA-B27 Transgenic Rats and the Effect of Erap1 Deletion.Epigenetic and gene expression analysis of ankylosing spondylitis-associated loci implicate immune cells and the gut in the disease pathogenesis.Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank.10 Years of GWAS Discovery: Biology, Function, and Translation.Pathogenesis of ankylosing spondylitis - recent advances and future directions.New insights toward the pathogenesis of ankylosing spondylitis; genetic variations and epigenetic modifications.Functional Genomics and Its Bench-to-Bedside Translation Pertaining to the Identified Susceptibility Alleles and Loci in Ankylosing Spondylitis.New insights into the understanding of MHC associations with immune-mediated disorders.Pain in ankylosing spondylitis: a neuro-immune collaboration.The Ankylosing Spondylitis-associated HLA-B*2705 presents a B*0702-restricted EBV epitope and sustains the clonal amplification of cytotoxic T cells in patients.The interplay between HLA-B27 and ERAP1/ERAP2 aminopeptidases: from anti-viral protection to spondyloarthritis.The Role of Conformational Dynamics in Antigen Trimming by Intracellular Aminopeptidases.Cross-phenotype association mapping of the MHC identifies genetic variants that differentiate psoriatic arthritis from psoriasis.Ethnicity and disease severity in ankylosing spondylitis a cross-sectional analysis of three ethnic groups.Immunogenetic Factors in Early Immune Control of Human Immunodeficiency Virus Type 1 (HIV-1) Infection: Evaluation of HLA Class I Amino Acid Variants in Two African PopulationsGenetic Variants in ERAP1 and ERAP2 Associated With Immune-Mediated Diseases Influence Protein Expression and the Isoform Profile.Mice expressing human ERAP1 variants associated with ankylosing spondylitis have altered T-cell repertoires and NK cell functions, as well as increased in utero and perinatal mortality.Exploiting non-canonical translation to identify new targets for T cell-based cancer immunotherapy.Progress of genome-wide association studies of ankylosing spondylitis.Crystal structure of a polypeptide's C-terminus in complex with the regulatory domain of ER aminopeptidase 1.The genetic associations of acute anterior uveitis and their overlap with the genetics of ankylosing spondylitis.Evidence for a second ankylosing spondylitis-associated RUNX3 regulatory polymorphism.'MHC-I-opathy'-unified concept for spondyloarthritis and Behçet disease.ERAP1 and HLA-C interaction in inflammatory bowel disease in the Spanish population.Novel HLA class I associations with HIV-1 control in a unique genetically admixed population.Non-classical human leucocyte antigens in ankylosing spondylitis: possible association with HLA-E and HLA-F.Recent advances in ankylosing spondylitis: understanding the disease and managementHow ERAP1 and ERAP2 Shape the Peptidomes of Disease-Associated MHC-I ProteinsERAP1 deficient mice have reduced Type 1 regulatory T cells and develop skeletal and intestinal features of Ankylosing SpondylitisDistinct mechanisms survey the structural integrity of HLA-B*27:05 intracellularly and at the surfaceProgress in our understanding of the pathogenesis of ankylosing spondylitis
P2860
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P2860
Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Major histocompatibility compl ...... further epistasis with ERAP1.
@ast
Major histocompatibility compl ...... further epistasis with ERAP1.
@en
type
label
Major histocompatibility compl ...... further epistasis with ERAP1.
@ast
Major histocompatibility compl ...... further epistasis with ERAP1.
@en
prefLabel
Major histocompatibility compl ...... further epistasis with ERAP1.
@ast
Major histocompatibility compl ...... further epistasis with ERAP1.
@en
P2093
P2860
P50
P356
P1476
Major histocompatibility compl ...... further epistasis with ERAP1.
@en
P2093
Adrian Cortes
Benedicte A Lie
Bryan Paul Wordsworth
C Lopez-Larrea
Claire Farrah
Consuelo Romero-Sánchez
Dirk Elewaut
Fernando M Pimentel-Santos
Francisco J Blanco
Gilles Chiocchia
P2860
P2888
P356
10.1038/NCOMMS8146
P407
P50
P577
2015-05-21T00:00:00Z