Saposin B is the dominant saposin that facilitates lipid binding to human CD1d molecules. - sprookjes - yvandenbroek - TriplyDB

Saposin B is the dominant saposin that facilitates lipid binding to human CD1d molecules.

Saposin B is the dominant saposin that facilitates lipid binding to human CD1d molecules.

http://www.wikidata.org/entity/Q35720184

about

Calreticulin controls the rate of assembly of CD1d molecules in the endoplasmic reticulum How do natural killer T cells help B cells?Synthetic glycolipid activators of natural killer T cells as immunotherapeutic agents Recognition of Microbial Glycolipids by Natural Killer T Cells Immunological cells and functions in Gaucher disease Insights into the Membrane Interactions of the Saposin-Like Proteins Na-SLP-1 and Ac-SLP-1 from Human and Dog Hookworm Neurological deficits and glycosphingolipid accumulation in saposin B deficient mice.Natural lipid ligands associated with human CD1d targeted to different subcellular compartments Lipid and glycolipid antigens of CD1d-restricted natural killer T cells.Regulation of CD1 antigen-presenting complex stability.A threonine-based targeting signal in the human CD1d cytoplasmic tail controls its functional expression Lipid antigens in immunity.Primary deficiency of microsomal triglyceride transfer protein in human abetalipoproteinemia is associated with loss of CD1 function.The effect of intracellular trafficking of CD1d on the formation of TCR repertoire of NKT cells.Fine tuning by human CD1e of lipid-specific immune responses.Quantitative microarray analysis of intact glycolipid-CD1d interaction and correlation with cell-based cytokine production Saposins utilize two strategies for lipid transfer and CD1 antigen presentation The structural and functional role of myelin fast-migrating cerebrosides: pathological importance in multiple sclerosis.Regulation of the actin cytoskeleton by Rho kinase controls antigen presentation by CD1d.Molecular imaging of membrane interfaces reveals mode of beta-glucosidase activation by saposin C.Deciphering the role of CD1e protein in mycobacterial phosphatidyl-myo-inositol mannosides (PIM) processing for presentation by CD1b to T lymphocytes.Anti-tumor potential of type-I NKT cells against CD1d-positive and CD1d-negative tumors in humans Endocytic pH regulates cell surface localization of glycolipid antigen loaded CD1d complexes Hiding lipid presentation: viral interference with CD1d-restricted invariant natural killer T (iNKT) cell activation Role for lysosomal phospholipase A2 in iNKT cell-mediated CD1d recognition.B cell receptor-mediated uptake of CD1d-restricted antigen augments antibody responses by recruiting invariant NKT cell help in vivo Natural killer T cells in health and disease.CD1 mediated T cell recognition of glycolipids.Dynamics of the antigen-binding grooves in CD1 proteins: reversible hydrophobic collapse in the lipid-free state.CD1d presentation of glycolipids.CD1d-restricted glycolipid antigens: presentation principles, recognition logic and functional consequences.Kinetics and cellular site of glycolipid loading control the outcome of natural killer T cell activation Saposins modulate human invariant Natural Killer T cells self-reactivity and facilitate lipid exchange with CD1d molecules during antigen presentation.UVB-induced skin inflammation and cutaneous tissue injury is dependent on the MHC class I-like protein, CD1d The immunological functions of saposins.Primary immunodeficiency associated with defects in CD1 and CD1-restricted T cells.Interplay between carbohydrate and lipid in recognition of glycolipid antigens by natural killer T cells.Molecular basis of lipid antigen presentation by CD1d and recognition by natural killer T cells.Invariant natural killer T cells in adipose tissue: novel regulators of immune-mediated metabolic disease.Optimizing NKT cell ligands as vaccine adjuvants

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P2860

Saposin B is the dominant saposin that facilitates lipid binding to human CD1d molecules.

http://www.wikidata.org/entity/Q35720184

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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2007年论文

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2007年论文

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name

Saposin B is the dominant saposin that facilitates lipid binding to human CD1d molecules.

@ast

Saposin B is the dominant saposin that facilitates lipid binding to human CD1d molecules.

@en

type

label

Saposin B is the dominant saposin that facilitates lipid binding to human CD1d molecules.

@ast

Saposin B is the dominant saposin that facilitates lipid binding to human CD1d molecules.

@en

prefLabel

Saposin B is the dominant saposin that facilitates lipid binding to human CD1d molecules.

@ast

Saposin B is the dominant saposin that facilitates lipid binding to human CD1d molecules.

@en

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P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Saposin B is the dominant saposin that facilitates lipid binding to human CD1d molecules.

@en

P2093

Jenny Gumperz

http://www.w3.org/2001/XMLSchema#string

Pansy Tsang

http://www.w3.org/2001/XMLSchema#string

Peter Cresswell

http://www.w3.org/2001/XMLSchema#string

Petr A Illarionov

http://www.w3.org/2001/XMLSchema#string

Suk-Jo Kang

http://www.w3.org/2001/XMLSchema#string

Weiming Yuan

http://www.w3.org/2001/XMLSchema#string

Xiaoyang Qi

http://www.w3.org/2001/XMLSchema#string

P2860

Crystal structure of saposin B reveals a dimeric shell for lipid binding

Mycobacterium tuberculosis pks12 produces a novel polyketide presented by CD1c to T cells

Crystal structures of saposins A and C

CD1: antigen presentation and T cell function

CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides

Lipid-protein interactions: biosynthetic assembly of CD1 with lipids in the endoplasmic reticulum is evolutionarily conserved

Separate pathways for antigen presentation by CD1 molecules.

Cellular uptake of saposin (SAP) precursor and lysosomal delivery by the low density lipoprotein receptor-related protein (LRP).

Editing of CD1d-bound lipid antigens by endosomal lipid transfer proteins.

Principles of lysosomal membrane digestion: stimulation of sphingolipid degradation by sphingolipid activator proteins and anionic lysosomal lipids.

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104

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6435588

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17372201

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1838443

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