AID in somatic hypermutation and class switch recombination.
about
APOBEC3 proteins mediate the clearance of foreign DNA from human cellsThe RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substratesMutational processes molding the genomes of 21 breast cancersSR proteins in vertical integration of gene expression from transcription to RNA processing to translationPhysiology of the read-write genomeThe APOBEC3 family of retroelement restriction factorsRelated Mechanisms of Antibody Somatic Hypermutation and Class Switch RecombinationThe interaction between AID and CIB1 is nonessential for antibody gene diversification by gene conversion or class switch recombinationTemporal regulation of Ig gene diversification revealed by single-cell imaging.A regulatory role for NBS1 in strand-specific mutagenesis during somatic hypermutationAttracting AID to targets of somatic hypermutation.Unique DNA repair gene variations and potential associations with the primary antibody deficiency syndromes IgAD and CVIDGeneration and repair of AID-initiated DNA lesions in B lymphocytes.Epstein-Barr virus (EBV)-associated epithelial and non-epithelial lesions of the oral cavity.Classical Mus musculus Igκ enhancers support transcription but not high level somatic hypermutation from a V-lambda promoter in chicken DT40 cells.Repression of human activation induced cytidine deaminase by miR-93 and miR-155.The origins of vertebrate adaptive immunity.Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancerA major deletion in the Vκ-Jκ intervening region results in hyperelevated transcription of proximal Vκ genes and a severely restricted repertoire.Evidence for APOBEC3B mutagenesis in multiple human cancersTargeting of somatic hypermutation.The pattern of somatic hypermutation of Ig genes is altered when p53 is inactivated.Antiviral protein APOBEC3G localizes to ribonucleoprotein complexes found in P bodies and stress granulesDNA polymerase eta is the sole contributor of A/T modifications during immunoglobulin gene hypermutation in the mouse.Dissecting the clonal origins of childhood acute lymphoblastic leukemia by single-cell genomics.Mechanism and regulation of class switch recombinationAn intrinsic propensity of murine peritoneal B1b cells to switch to IgA in presence of TGF-β and retinoic acid.Separation of mutational and transcriptional enhancers in Ig genes.R-loop-mediated genomic instability is caused by impairment of replication fork progressionSequence dependence of chromosomal R-loops at the immunoglobulin heavy-chain Smu class switch regionInhibition of the catalytic function of activation-induced cytidine deaminase promotes apoptosis of germinal center B cells in BXD2 mice.Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice.Regulation of AID expression in the immune responseDown-regulation of DNA polymerase beta accompanies somatic hypermutation in human BL2 cell linesAberrant immunoglobulin class switch recombination and switch translocations in activated B cell-like diffuse large B cell lymphoma.Methylcytosine and normal cytosine deamination by the foreign DNA restriction enzyme APOBEC3AAlkyladenine DNA glycosylase (Aag) in somatic hypermutation and class switch recombinationCreation of chimeric human/rabbit APOBEC1 with HIV-1 restriction and DNA mutation activities.DNA repair in antibody somatic hypermutation.AID-mediated diversification within the IgL locus of chicken DT40 cells is restricted to the transcribed IgL gene.
P2860
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P2860
AID in somatic hypermutation and class switch recombination.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
AID in somatic hypermutation and class switch recombination.
@ast
AID in somatic hypermutation and class switch recombination.
@en
type
label
AID in somatic hypermutation and class switch recombination.
@ast
AID in somatic hypermutation and class switch recombination.
@en
prefLabel
AID in somatic hypermutation and class switch recombination.
@ast
AID in somatic hypermutation and class switch recombination.
@en
P2093
P1476
AID in somatic hypermutation and class switch recombination.
@en
P2093
Frederick Alt
Simonne Longerich
Ursula Storb
Uttiya Basu
P304
P356
10.1016/J.COI.2006.01.008
P577
2006-02-07T00:00:00Z