Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines.
about
Using Pharmacogenomic Databases for Discovering Patient-Target Genes and Small Molecule Candidates to Cancer TherapyInduced protein degradation: an emerging drug discovery paradigm.Systematic high-content genome-wide RNAi screens of endothelial cell migration and morphology.'Big data' approaches for novel anti-cancer drug discovery.ATR inhibitors as a synthetic lethal therapy for tumours deficient in ARID1A.Mapping genetic vulnerabilities reveals BTK as a novel therapeutic target in oesophageal cancer.Seed-effect modeling improves the consistency of genome-wide loss-of-function screens and identifies synthetic lethal vulnerabilities in cancer cells.Molecular genetics of osteosarcoma.Advances and challenges in targeting FGFR signalling in cancer.CancerGD: A Resource for Identifying and Interpreting Genetic Dependencies in Cancer.CRISPR/Cas9 mutagenesis invalidates a putative cancer dependency targeted in on-going clinical trials.High-throughput RNAi screen for essential genes and drug synergistic combinations in colorectal cancer.ATR Is a Therapeutic Target in Synovial Sarcoma.The phosphatase PTPRG controls FGFR1 activity and influences sensitivity to FGFR kinase inhibitors.A high throughput method to study the physiology of E2:ERα signaling in breast cancer cells.Targeting the Vulnerability of RB Tumor Suppressor Loss in Triple-Negative Breast Cancer.Identifying Genetic Dependencies in Cancer by Analyzing siRNA Screens in Tumor Cell Line Panels.Modeling Therapy Resistance in BRCA1/2-Mutant Cancers.Functional genomics identifies specific vulnerabilities in PTEN-deficient breast cancer.FamPlex: a resource for entity recognition and relationship resolution of human protein families and complexes in biomedical text mining.Applications of RNA Indexes for Precision Oncology in Breast CancerIdentification of highly penetrant Rb-related synthetic lethal interactions in triple negative breast cancer
P2860
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P2860
Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines.
@ast
Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines.
@en
type
label
Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines.
@ast
Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines.
@en
prefLabel
Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines.
@ast
Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines.
@en
P2093
P2860
P50
P1433
P1476
Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines.
@en
P2093
Aditi Gulati
Bissan Al-Lazikani
Chris T Williamson
David A Quigley
Harriet Holme
Helen N Pemberton
Ilirjana Bajrami
Irene Y Chong
Jessica Frankum
P2860
P304
P356
10.1016/J.CELREP.2016.02.023
P50
P577
2016-03-02T00:00:00Z