Human African trypanosomiasis: pharmacological re-engagement with a neglected disease.
about
SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasisFexinidazole--a new oral nitroimidazole drug candidate entering clinical development for the treatment of sleeping sicknessManagement of trypanosomiasis and leishmaniasisNuclear DBF-2-related kinases are essential regulators of cytokinesis in bloodstream stage Trypanosoma bruceiLeishmania trypanothione synthetase-amidase structure reveals a basis for regulation of conflicting synthetic and hydrolytic activitiesThe Potential Use of Natural and Structural Analogues of Antimicrobial Peptides in the Fight against Neglected Tropical DiseasesA current analysis of chemotherapy strategies for the treatment of human African trypanosomiasisNovel amidines and analogues as promising agents against intracellular parasites: a systematic reviewIn vivo imaging of trypanosome-brain interactions and development of a rapid screening test for drugs against CNS stage trypanosomiasisMelarsoprol cyclodextrin inclusion complexes as promising oral candidates for the treatment of human African trypanosomiasisNatively Inhibited Trypanosoma brucei Cathepsin B Structure Determined by Using an X-ray LaserCrystal Structures of TbCatB and Rhodesain, Potential Chemotherapeutic Targets and Major Cysteine Proteases of Trypanosoma bruceiHigh-resolution structures ofTrypanosoma bruceipteridine reductase ligand complexes inform on the placement of new molecular entities in the active site of a potential drug targetCrystal Structures of T. b. rhodesiense Adenosine Kinase Complexed with Inhibitor and Activator: Implications for Catalysis and HyperactivationStructures of adenosine kinase fromTrypanosoma brucei bruceiStructure-Based Design and Synthesis of Antiparasitic Pyrrolopyrimidines Targeting Pteridine Reductase 1Binding to large enzyme pockets: small-molecule inhibitors of trypanothione reductaseDyes, trypanosomiasis and DNA: a historical and critical reviewTargeting pathogen metabolism without collateral damage to the hostComplete in vitro life cycle of Trypanosoma congolense: development of genetic toolsRegulated expression of an essential allosteric activator of polyamine biosynthesis in African trypanosomesNECT is next: implementing the new drug combination therapy for Trypanosoma brucei gambiense sleeping sicknessNovel naphthalene-based inhibitors of Trypanosoma brucei RNA editing ligase 1Adenosine Kinase of T. b. Rhodesiense identified as the putative target of 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine using chemical proteomicsA molecular mechanism for eflornithine resistance in African trypanosomesShould I get screened for sleeping sickness? A qualitative study in Kasai province, Democratic Republic of CongoUntargeted metabolomics reveals a lack of synergy between nifurtimox and eflornithine against Trypanosoma bruceiLapatinib-binding protein kinases in the African trypanosome: identification of cellular targets for kinase-directed chemical scaffoldsExploring the Trypanosoma brucei Hsp83 potential as a target for structure guided drug designHandling uncertainty in dynamic models: the pentose phosphate pathway in Trypanosoma bruceiCrovirin, a snake venom cysteine-rich secretory protein (CRISP) with promising activity against Trypanosomes and LeishmaniaGenome-Wide Comparative Analysis of Chemosensory Gene Families in Five Tsetse Fly SpeciesAntitrypanosomal Activities and Mechanisms of Action of Novel Tetracyclic Iridoids from Morinda lucida Benth.Global metabolic responses of mice to Trypanosoma brucei brucei infectionSpermine synthase deficiency leads to deafness and a profound sensitivity to alpha-difluoromethylornithine.Counterflow dielectrophoresis for trypanosome enrichment and detection in blood.Investigation of trypanothione reductase as a drug target in Trypanosoma brucei.Assessing the trypanocidal potential of natural and semi-synthetic diketopiperazines from two deep water marine-derived fungi.Use of reconstituted metabolic networks to assist in metabolomic data visualization and miningVirtual fragment screening for novel inhibitors of 6-phosphogluconate dehydrogenase.
P2860
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P2860
Human African trypanosomiasis: pharmacological re-engagement with a neglected disease.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Human African trypanosomiasis: pharmacological re-engagement with a neglected disease.
@ast
Human African trypanosomiasis: pharmacological re-engagement with a neglected disease.
@en
type
label
Human African trypanosomiasis: pharmacological re-engagement with a neglected disease.
@ast
Human African trypanosomiasis: pharmacological re-engagement with a neglected disease.
@en
prefLabel
Human African trypanosomiasis: pharmacological re-engagement with a neglected disease.
@ast
Human African trypanosomiasis: pharmacological re-engagement with a neglected disease.
@en
P2093
P2860
P356
P1476
Human African trypanosomiasis: pharmacological re-engagement with a neglected disease
@en
P2093
P2860
P304
P356
10.1038/SJ.BJP.0707354
P407
P577
2007-07-09T00:00:00Z