Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases. - sprookjes - yvandenbroek - TriplyDB

Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases.

Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases.

http://www.wikidata.org/entity/Q36827351

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Plasmodium falciparum CRK4 directs continuous rounds of DNA replication during schizogony p27Kip1 promotes invadopodia turnover and invasion through the regulation of the PAK1/Cortactin pathway.Low-grade slightly elevated and polypoid colorectal adenomas display differential β-catenin-TCF/LEF activity, c-Myc, and cyclin D1 expression.Overexpressed HDAC4 is associated with poor survival and promotes tumor progression in esophageal carcinoma Interchangeable Roles for E2F Transcriptional Repression by the Retinoblastoma Protein and p27KIP1-Cyclin-Dependent Kinase Regulation in Cell Cycle Control and Tumor Suppression.Progress with palbociclib in breast cancer: latest evidence and clinical considerations.Diallyl Trisulfide Inhibits Growth of NCI-H460 in Vitro and in Vivo, and Ameliorates Cisplatin-Induced Oxidative Injury in the Treatment of Lung Carcinoma in Xenograft Mice.CXCR7 Participates in CXCL12-mediated Cell Cycle and Proliferation Regulation in Mouse Neural Progenitor Cells.Cell cycle proteins as promising targets in cancer therapy Cdk4 regulates adult neural stem cell proliferation and differentiation in response to insulin-IRS2 signals.CDK6 protects epithelial ovarian cancer from platinum-induced death via FOXO3 regulation.A novel series of N-(pyridin-2-yl)-4-(thiazol-5-yl)pyrimidin-2-amines as highly potent CDK4/6 inhibitors.Palbociclib has antitumour effects on Pten-deficient endometrial neoplasias.Regulation of small GTPase activity by G1 cyclins.Moving messages in the developing brain-emerging roles for mRNA transport and local translation in neural stem cells.Understanding cell cycle and cell death regulation provides novel weapons against human diseases.MYC Modulation around the CDK2/p27/SKP2 Axis Checkpoints of apicomplexan cell division identified in Toxoplasma gondii.Cyclin D3 deficiency inhibits skin tumor development, but does not affect normal keratinocyte proliferation.Regulation of the Candida albicans Hypha-Inducing Transcription Factor Ume6 by the CDK1 Cyclins Cln3 and Hgc1.Effects of roniciclib in preclinical models of anaplastic thyroid cancer.Cytoplasmic cyclin D1 controls the migration and invasiveness of mantle lymphoma cells.Hormone-induced DNA damage response and repair mediated by cyclin D1 in breast and prostate cancer.Fibroblast Growth Factor 21 Promotes C2C12 Cells Myogenic Differentiation by Enhancing Cell Cycle Exit.Ensemble-based modeling and rigidity decomposition of allosteric interaction networks and communication pathways in cyclin-dependent kinases: Differentiating kinase clients of the Hsp90-Cdc37 chaperone.Cdk7 Is Required for Activity-Dependent Neuronal Gene Expression, Long-Lasting Synaptic Plasticity and Long-Term Memory.p16Ink4a and p21Cip1/Waf1 promote tumour growth by enhancing myeloid-derived suppressor cells chemotaxis.Aminopurvalanol A, a Potent, Selective, and Cell Permeable Inhibitor of Cyclins/Cdk Complexes, Causes the Reduction of in Vitro Fertilizing Ability of Boar Spermatozoa, by Negatively Affecting the Capacitation-Dependent Actin Polymerization.Cyclin D-CDK4 kinase destabilizes PD-L1 via cullin 3-SPOP to control cancer immune surveillance.6-(Methylsulfonyl) hexyl isothiocyanate as potential chemopreventive agent: molecular and cellular profile in leukaemia cell lines.Insulin regulation of gluconeogenesis.Loss of Cyclin-dependent Kinase 2 in the Pancreas Links Primary β-Cell Dysfunction to Progressive Depletion of β-Cell Mass and Diabetes.Eriocitrin from lemon suppresses the proliferation of human hepatocellular carcinoma cells through inducing apoptosis and arresting cell cycle.Targeting Sphingosine Kinase Isoforms Effectively Reduces Growth and Survival of Neoplastic Mast Cells With D816V-KIT.Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration.Diallyl trisulfide suppresses tumor growth through the attenuation of Nrf2/Akt and activation of p38/JNK and potentiates cisplatin efficacy in gastric cancer treatment.Identification of potential diagnostic and prognostic biomarkers in non-small cell lung cancer based on microarray data.Role of p27Kip1 as a transcriptional regulator.Overexpression of p62 is associated with poor prognosis and aggressive phenotypes in osteosarcoma.Activity of roniciclib in medullary thyroid cancer.

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P2860

Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases.

http://www.wikidata.org/entity/Q36827351

description

2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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2016年论文

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2016年论文

@zh-cn

name

Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases.

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type

label

Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases.

@en

prefLabel

Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases.

@en

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Nature Reviews Molecular Cell Biology

P1476

Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases.

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P2093

Marcos Malumbres

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Per Hydbring

http://www.w3.org/2001/XMLSchema#string

Piotr Sicinski

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P2860

Cdk1 targets Srs2 to complete synthesis-dependent strand annealing and to promote recombinational repair

PD 0332991, a selective cyclin D kinase 4/6 inhibitor, preferentially inhibits proliferation of luminal estrogen receptor-positive human breast cancer cell lines in vitro

The p16(INK4a) tumour suppressor protein inhibits alphavbeta3 integrin-mediated cell spreading on vitronectin by blocking PKC-dependent localization of alphavbeta3 to focal contacts.

Cell cycle-regulated phosphorylation of p220(NPAT) by cyclin E/Cdk2 in Cajal bodies promotes histone gene transcription

Induction of p19INK4d in response to ultraviolet light improves DNA repair and confers resistance to apoptosis in neuroblastoma cells

A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells

CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair

Cyclin-dependent kinases regulate epigenetic gene silencing through phosphorylation of EZH2

Cdk6 blocks myeloid differentiation by interfering with Runx1 DNA binding and Runx1-C/EBPalpha interaction

Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase

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10.1038/NRM.2016.27

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17

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