Genetic basis of HDL variation in 129/SvImJ and C57BL/6J mice: importance of testing candidate genes in targeted mutant mice
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Mapping and Congenic Dissection of Genetic Loci Contributing to Hyperglycemia and Dyslipidemia in Mice.Genetic linkage of hyperglycemia and dyslipidemia in an intercross between BALB/cJ and SM/J Apoe-deficient mouse strains.Atherosclerosis susceptibility Loci identified in an extremely atherosclerosis-resistant mouse strain.A forest-based feature screening approach for large-scale genome data with complex structures.Novel ENU-induced point mutation in scavenger receptor class B, member 1, results in liver specific loss of SCARB1 protein.Combining genome-wide data from humans and animal models of dyslipidemia and atherosclerosis.Untangling HDL quantitative trait loci on mouse chromosome 5 and identifying Scarb1 and Acads as the underlying genesGenetic, epigenetic, and gene-by-diet interaction effects underlie variation in serum lipids in a LG/JxSM/J murine modelIntegration of QTL and bioinformatic tools to identify candidate genes for triglycerides in mice.Body Composition QTLs Identified in Intercross Populations Are Reproducible in Consomic Mouse StrainsUsing bioinformatics and systems genetics to dissect HDL-cholesterol genetics in an MRL/MpJ x SM/J intercrossIdentification of novel mouse genes conferring posthypoxic pauses.Recalculation of 23 mouse HDL QTL datasets improves accuracy and allows for better candidate gene analysis.Identification of a novel polymorphism in X-linked sterol-4-alpha-carboxylate 3-dehydrogenase (Nsdhl) associated with reduced high-density lipoprotein cholesterol levels in I/LnJ mice.Four additional mouse crosses improve the lipid QTL landscape and identify Lipg as a QTL gene.Farp2 and Stk25 are candidate genes for the HDL cholesterol locus on mouse chromosome 1.Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice.A graphical weighted power improving multiplicity correction approach for SNP selections.Deletion of Nrip1 extends female mice longevity, increases autophagy, and delays cell senescence.
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P2860
Genetic basis of HDL variation in 129/SvImJ and C57BL/6J mice: importance of testing candidate genes in targeted mutant mice
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 04 September 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Genetic basis of HDL variation ...... genes in targeted mutant mice
@en
Genetic basis of HDL variation ...... genes in targeted mutant mice.
@nl
type
label
Genetic basis of HDL variation ...... genes in targeted mutant mice
@en
Genetic basis of HDL variation ...... genes in targeted mutant mice.
@nl
prefLabel
Genetic basis of HDL variation ...... genes in targeted mutant mice
@en
Genetic basis of HDL variation ...... genes in targeted mutant mice.
@nl
P2093
P2860
P1476
Genetic basis of HDL variation ...... genes in targeted mutant mice
@en
P2093
Aihong Zhang
Allison Cox
Beverly Paigen
Shirng-Wern Tsaih
Susan Sheehan
Xiaosong Wang
P2860
P304
P356
10.1194/JLR.M800411-JLR200
P50
P577
2008-09-04T00:00:00Z