Minor intron splicing is regulated by FUS and affected by ALS-associated FUS mutants
about
Characterization of genetic loss-of-function of Fus in zebrafish.Functional interaction between FUS and SMN underlies SMA-like splicing changes in wild-type hFUS mice.Hypoxia is a Key Driver of Alternative Splicing in Human Breast Cancer Cells.TDP-43 and FUS en route from the nucleus to the cytoplasm.RNA-sequencing of a mouse-model of spinal muscular atrophy reveals tissue-wide changes in splicing of U12-dependent introns.Succession of splicing regulatory elements determines cryptic 5΄ss functionality.Faulty RNA splicing: consequences and therapeutic opportunities in brain and muscle disorders.Failure to Deliver and Translate-New Insights into RNA Dysregulation in ALS.The minor spliceosome could be the major key for FUS/TLS mutants in ALSNucleic acid binding proteins affect the subcellular distribution of phosphorothioate antisense oligonucleotides.Motor Neuron Gene Therapy: Lessons from Spinal Muscular Atrophy for Amyotrophic Lateral Sclerosis.Mutations in the U11/U12-65K protein associated with isolated growth hormone deficiency lead to structural destabilization and impaired binding of U12 snRNA.CRISPR-Trap: a clean approach for the generation of gene knockouts and gene replacements in human cells.Matrin3 binds directly to intronic pyrimidine-rich sequences and controls alternative splicing.SMN regulation in SMA and in response to stress: new paradigms and therapeutic possibilities.Dysregulated molecular pathways in amyotrophic lateral sclerosis-frontotemporal dementia spectrum disorder.[Pre-mRNA splicing: when the spliceosome loses ground].The Role of Post-Translational Modifications on Prion-Like Aggregation and Liquid-Phase Separation of FUS.Functional Interplay between Small Non-Coding RNAs and RNA Modification in the Brain.Unexpected similarities between C9ORF72 and sporadic forms of ALS/FTD suggest a common disease mechanism
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Minor intron splicing is regulated by FUS and affected by ALS-associated FUS mutants
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on June 2016
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Minor intron splicing is regulated by FUS and affected by ALS-associated FUS mutants
@en
Minor intron splicing is regulated by FUS and affected by ALS-associated FUS mutants.
@nl
type
label
Minor intron splicing is regulated by FUS and affected by ALS-associated FUS mutants
@en
Minor intron splicing is regulated by FUS and affected by ALS-associated FUS mutants.
@nl
prefLabel
Minor intron splicing is regulated by FUS and affected by ALS-associated FUS mutants
@en
Minor intron splicing is regulated by FUS and affected by ALS-associated FUS mutants.
@nl
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P2860
P50
P356
P1433
P1476
Minor intron splicing is regulated by FUS and affected by ALS-associated FUS mutants
@en
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Daniel Jutzi
Jolanda Stettler
Martino Colombo
Rémy Bruggmann
Silvia C Lenzken
Silvia Ml Barabino
P2860
P304
P356
10.15252/EMBJ.201593791
P407
P577
2016-06-01T00:00:00Z