The mouse fibula as a suitable bone for the study of functional adaptation to mechanical loading.
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Sost down-regulation by mechanical strain in human osteoblastic cells involves PGE2 signaling via EP4Sclerostin and occlusion: A brief reviewRegulation of Wnt/β-catenin signaling within and from osteocytesFunctional adaptation to mechanical loading in both cortical and cancellous bone is controlled locally and is confined to the loaded bones.Loading-related regulation of gene expression in bone in the contexts of estrogen deficiency, lack of estrogen receptor alpha and disuseSclerostin: current knowledge and future perspectives.The Contribution of Experimental in vivo Models to Understanding the Mechanisms of Adaptation to Mechanical Loading in BoneMechanical loading-related bone gain is enhanced by tamoxifen but unaffected by fulvestrant in female miceRisedronate does not reduce mechanical loading-related increases in cortical and trabecular bone mass in miceCortical bone resorption following muscle paralysis is spatially heterogeneous.Loading-related regulation of transcription factor EGR2/Krox-20 in bone cells is ERK1/2 protein-mediated and prostaglandin, Wnt signaling pathway-, and insulin-like growth factor-I axis-dependentMechanical loading-related changes in osteocyte sclerostin expression in mice are more closely associated with the subsequent osteogenic response than the peak strains engendered.The effect of single extremity-vibration on the serum sclerostin level.The cyclooxygenase-2 selective inhibitor NS-398 does not influence trabecular or cortical bone gain resulting from repeated mechanical loading in female miceMale mice housed in groups engage in frequent fighting and show a lower response to additional bone loading than females or individually housed males that do not fight.Mechanical signaling for bone modeling and remodelingOsteocytes and WNT: the mechanical control of bone formation.Adaptive and Injury Response of Bone to Mechanical Loading.Accuracy and reproducibility of mouse cortical bone microporosity as quantified by desktop microcomputed tomography.Recombinant sclerostin antagonises effects of ex vivo mechanical loading in trabecular bone and increases osteocyte lacunar size.Histomorphometry and cortical robusticity of the adult human femur.Bone mechanobiology in mice: toward single-cell in vivo mechanomics.Canalization Leads to Similar Whole Bone Mechanical Function at Maturity in Two Inbred Strains of Mice.Deterioration of bone quality in the tibia and fibula in growing mice during skeletal unloading: gender-related differences.Regulation of Sclerostin Expression by Paracrine and Endocrine FactorsAnalysis of multiple bone responses to graded strains above functional levels, and to disuse, in mice in vivo show that the human Lrp5 G171V High Bone Mass mutation increases the osteogenic response to loading but that lack of Lrp5 activity reduces iMechanical Loading Differentially Affects Osteocytes in Fibulae from Lactating Mice Compared to Osteocytes in Virgin Mice: Possible Role for Lacuna Size
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The mouse fibula as a suitable bone for the study of functional adaptation to mechanical loading.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 14 January 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The mouse fibula as a suitable ...... ptation to mechanical loading.
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The mouse fibula as a suitable ...... ptation to mechanical loading.
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type
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The mouse fibula as a suitable ...... ptation to mechanical loading.
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The mouse fibula as a suitable ...... ptation to mechanical loading.
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The mouse fibula as a suitable ...... ptation to mechanical loading.
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The mouse fibula as a suitable ...... ptation to mechanical loading.
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P2093
P2860
P1433
P1476
The mouse fibula as a suitable ...... ptation to mechanical loading.
@en
P2093
Alaa Moustafa
Andrew Sunters
Joanna S Price
Lance E Lanyon
Leanne K Saxon
Victoria J Armstrong
P2860
P304
P356
10.1016/J.BONE.2008.12.026
P577
2009-01-14T00:00:00Z