Structure of pyrazole derivatives impact their affinity, stoichiometry, and cooperative interactions for CYP2E1 complexes.
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Structural basis for cooperative binding of azoles to CYP2E1 as interpreted through guided molecular dynamics simulations.Subcellular localization of rat CYP2E1 impacts metabolic efficiency toward common substrates.Functioning of drug-metabolizing microsomal cytochrome P450s: In silico probing of proteins suggests that the distal heme 'active site' pocket plays a relatively 'passive role' in some enzyme-substrate interactionsZebrafish have an ethanol-inducible hepatic 4-nitrophenol hydroxylase that is not CYP2E1-like.Cooperativity in CYP2E1 metabolism of acetaminophen and styrene mixtures.Spectroscopic studies of the cytochrome P450 reaction mechanisms.Cytochrome P450 structure-function: insights from molecular dynamics simulations.Biochar application increases sorption of nitrification inhibitor 3,4-dimethylpyrazole phosphate in soil.
P2860
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P2860
Structure of pyrazole derivatives impact their affinity, stoichiometry, and cooperative interactions for CYP2E1 complexes.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 27 June 2013
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vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Structure of pyrazole derivati ...... ractions for CYP2E1 complexes.
@en
Structure of pyrazole derivati ...... ractions for CYP2E1 complexes.
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type
label
Structure of pyrazole derivati ...... ractions for CYP2E1 complexes.
@en
Structure of pyrazole derivati ...... ractions for CYP2E1 complexes.
@nl
prefLabel
Structure of pyrazole derivati ...... ractions for CYP2E1 complexes.
@en
Structure of pyrazole derivati ...... ractions for CYP2E1 complexes.
@nl
P2093
P2860
P1476
Structure of pyrazole derivati ...... ractions for CYP2E1 complexes.
@en
P2093
Amber M Bradley
Grover P Miller
Jessica H Hartman
Martin D Perry
Ryan M Laddusaw
P2860
P356
10.1016/J.ABB.2013.06.011
P407
P577
2013-06-27T00:00:00Z