Posttranscriptional gene regulation by spatial rearrangement of the 3' untranslated region. - sprookjes - yvandenbroek - TriplyDB

Posttranscriptional gene regulation by spatial rearrangement of the 3' untranslated region.

Posttranscriptional gene regulation by spatial rearrangement of the 3' untranslated region.

http://www.wikidata.org/entity/Q37210527

about

Noisy splicing, more than expression regulation, explains why some exons are subject to nonsense-mediated mRNA decay Ago2/miRISC-mediated inhibition of CBP80/20-dependent translation and thereby abrogation of nonsense-mediated mRNA decay require the cap-associating activity of Ago2 A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay Unusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2 Mechanism of escape from nonsense-mediated mRNA decay of human beta-globin transcripts with nonsense mutations in the first exon Tracking and coordinating an international curation effort for the CCDS Project Human SP-A1 (SFTPA1) variant-specific 3' UTRs and poly(A) tail differentially affect the in vitro translation of a reporter gene Structural characterization of the Rous sarcoma virus RNA stability element Nonsense-mediated mRNA decay: novel mechanistic insights and biological impact Mechanism and regulation of the nonsense-mediated decay pathway The role of mammalian poly(A)-binding proteins in co-ordinating mRNA turnover The dharma of nonsense-mediated mRNA decay in mammalian cells Retroviral strategy to stabilize viral RNA Selection for reduced translation costs at the intronic 5' end in fungi A novel protein, Pho92, has a conserved YTH domain and regulates phosphate metabolism by decreasing the mRNA stability of PHO4 in Saccharomyces cerevisiae.Nonsense-mediated mRNA decay in humans at a glance Nonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the Story Organizing principles of mammalian nonsense-mediated mRNA decay Mutations in SMG9, Encoding an Essential Component of Nonsense-Mediated Decay Machinery, Cause a Multiple Congenital Anomaly Syndrome in Humans and Mice Eukaryotic initiation factor 4G suppresses nonsense-mediated mRNA decay by two genetically separable mechanisms UPF2 is a critical regulator of liver development, function and regeneration High-resolution mapping of expression-QTLs yields insight into human gene regulation.Large-scale clonal analysis reveals unexpected complexity in surface ectoderm morphogenesis Modulation of nonsense mediated decay by rapamycin Transcripts expressed using a bicistronic vector pIREShyg2 are sensitized to nonsense-mediated mRNA decay.Nucleosome deposition and DNA methylation may participate in the recognition of premature termination codon in nonsense-mediated mRNA decay.Expression proteomics of UPF1 knockdown in HeLa cells reveals autoregulation of hnRNP A2/B1 mediated by alternative splicing resulting in nonsense-mediated mRNA decay.Splicing-dependent NMD does not require the EJC in Schizosaccharomyces pombe Regulation of the mRNA half-life in breast cancer A novel phosphorylation-independent interaction between SMG6 and UPF1 is essential for human NMD.Preventing dangerous nonsense: selection for robustness to transcriptional error in human genes.Position of premature termination codons determines susceptibility of hERG mutations to nonsense-mediated mRNA decay in long QT syndrome A role for nonsense-mediated mRNA decay in plants: pathogen responses are induced in Arabidopsis thaliana NMD mutants.Nuclear import of cytoplasmic poly(A) binding protein restricts gene expression via hyperadenylation and nuclear retention of mRNA.Alternative polyadenylation and nonsense-mediated decay coordinately regulate the human HFE mRNA levels.Regulation of eukaryotic gene expression by the untranslated gene regions and other non-coding elements The CFTR frameshift mutation 3905insT and its effect at transcript and protein level.Poly(A) binding proteins: are they all created equal?A post-translational regulatory switch on UPF1 controls targeted mRNA degradation RNA decay modulates gene expression and controls its fidelity

P2860

Q21245331-E43BBCA7-A84B-43E5-AADA-ED92220BF595 Q24321947-09D18868-7163-4973-9B34-A5F3531EF137 Q24336651-4A3CD7C2-D952-4622-99B9-0197BD9C7888 Q24339439-7F25A67F-63BB-43EB-BE9F-B7A669AB5DF4 Q24613209-06561174-5D10-41D5-B2A0-DAEF8010356B Q24613989-EF34093A-5E09-47DD-B830-83075E11F45B Q24630060-330136C0-6E81-47C5-B925-4B35889B4239 Q24652241-EE8875BC-E668-4D58-9A94-3F5B502AEFDC Q26750271-B12E19EC-C761-4729-8A4E-81E2C96FE33C Q26771669-69F6A075-9A36-4D7C-97E0-15947A9949E0 Q27010244-804D6339-876F-4BE6-B7DC-57207F8B0022 Q27014757-138C5611-D31B-451E-944B-1E3B132BEA00 Q27022549-16C0F4B7-8120-461F-8C77-71AF78BDA1D4 Q27302027-79CD4DD6-D615-46A6-B636-A79BE281D608 Q27937239-CDFDF869-E8F3-47C2-BBC5-8FBD63C4C10A Q28077157-FC57D1F7-6BEF-4B7F-84DA-4E6C9E965029 Q28082699-75C75E97-725C-4EF2-9099-CA038411BCAE Q28302705-892D11B0-C888-4DFA-9079-1E5490B80853 Q28513439-93CFF76D-C648-42DA-B7F2-B1EA0D86F173 Q28542512-BBA9F73D-CF8D-474B-8A2F-6BD95951A688 Q28588810-854E9E3F-1310-455A-89C4-92B30D1A7112 Q33375030-ACC12CBB-44EE-4C5A-BABC-4E2CAF770A08 Q33406267-9E21C761-F1F3-426E-882C-7050BE706C14 Q33557383-CC075726-6362-438D-997A-461FD824A74E Q33591018-1633F5D7-4235-4019-9757-A82A36F6A04A Q33646294-7B3BCBF7-9DA1-4A41-B910-BC78986A5C31 Q33718674-0A4D23E1-6FA2-44E3-9D99-18063CCB4277 Q33878474-9155412A-7E6C-4BF4-9AA8-44FEFF587C8C Q34023658-32E22D4B-426A-419A-8548-F48688F32830 Q34044484-8D0B01AA-52A1-42E8-B2C3-CBAAEAB2D91A Q34055313-7AF6B154-C137-4EA2-96A7-B070049F0E71 Q34082145-DB934B66-1B4B-4338-BB88-214FDDEB36B8 Q34182070-77875E2D-782D-4A73-86FA-F55F0961D683 Q34190177-336CD41E-4507-471E-BAE8-8426603398AB Q34243757-7BE44862-B7FA-41B9-9AA7-45F0C9C6E098 Q34271240-DBBC14B0-F60E-4673-A660-4AC73AA8A2BA Q34328550-EF815A64-57CF-4BBE-9FDB-6033D615C8C3 Q34328667-3E50FD71-A41B-48CD-8931-40013D50E630 Q34342871-0136F7D9-2099-4BE9-98BA-BECB7E947E11 Q34364183-227356E1-994D-4B8A-B01E-C9E428F4369D

P2860

Posttranscriptional gene regulation by spatial rearrangement of the 3' untranslated region.

http://www.wikidata.org/entity/Q37210527

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on April 2008

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Posttranscriptional gene regul ...... of the 3' untranslated region.

@en

Posttranscriptional gene regul ...... of the 3' untranslated region.

@nl

type

label

Posttranscriptional gene regul ...... of the 3' untranslated region.

@en

Posttranscriptional gene regul ...... of the 3' untranslated region.

@nl

prefLabel

Posttranscriptional gene regul ...... of the 3' untranslated region.

@en

Posttranscriptional gene regul ...... of the 3' untranslated region.

@nl

P1433

Q37210527-10E092E9-0D21-41F6-A2D5-9996A06404D2

P1476

Q37210527-1EB711A0-699E-4292-BDD7-B35D74B05F8C

P2093

Q37210527-06EFED0D-2A18-49EE-9F32-8E67D771768F

Q37210527-4F3DC494-03DD-4E9D-AE7B-5ECD21B3D10D

Q37210527-4FEA65E6-BF7B-42AB-91E8-4FE7A0E198AE

Q37210527-DEC7E84F-E364-4174-B93D-B13E6A519DFB

P2860

Q37210527-03761B4F-EAFA-4521-A0E5-1B4DD240544C

Q37210527-076B0227-C3AA-43AB-B7CF-60FF440C5209

Q37210527-08D09621-3BAA-4FB2-8A0E-716D5B05086B

Q37210527-0F5F9C77-BF91-423C-9461-7959B7DC660D

Q37210527-114C1A2E-588B-48B6-B2FF-B35039DC2E5A

Q37210527-156FD736-4B23-4A33-A5F0-F3E0CDAA0964

Q37210527-16FE7A18-940A-4010-B068-72252417D604

Q37210527-19B5E5AD-5B2C-4B88-BEBE-FB02458B41B9

Q37210527-20687965-BA8D-4334-B5CB-74F6ACBE60F2

Q37210527-21BE82B4-141D-4896-AECA-2E84C44D7DFB

P304

Q37210527-DA6BE6A3-0A07-4A99-8586-9E472A4CEC46

P31

Q37210527-DE1D692F-3CD7-4C74-9764-B5B1444ACDD9

P356

Q37210527-6D00165A-3E89-4540-A1FC-73319FB7B37C

P407

Q37210527-6E165C18-342A-4DEC-A9EB-F626DF6731C9

P433

Q37210527-4F5D3755-14FC-4EA0-9C2D-93F760F6089E

P478

Q37210527-C977BAC0-DDDC-44CE-83B9-5F0446AE08CE

P50

Q37210527-40816AE0-8C8E-49CB-861D-D2FBF407C047

P577

Q37210527-89BCA8B7-D303-4EDF-8482-7EA1E64C9707

P5875

Q37210527-E651298E-682E-423A-BD29-0A9C26FEA367

P698

Q37210527-4600C53F-877D-4CB8-8380-E147020651AC

P932

Q37210527-FA2EA33F-8F92-4BC0-9A22-80A4C3529578

P356

JOURNAL.PBIO.0060092

P1433

P1476

Posttranscriptional gene regul ...... of the 3' untranslated region.

@en

P2093

Andrea B Eberle

http://www.w3.org/2001/XMLSchema#string

Hansruedi Mathys

http://www.w3.org/2001/XMLSchema#string

Lukas Stalder

http://www.w3.org/2001/XMLSchema#string

Rodolfo Zamudio Orozco

http://www.w3.org/2001/XMLSchema#string

P2860

Characterization of the biochemical properties of the human Upf1 gene product that is involved in nonsense-mediated mRNA decay.

Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon

Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20

Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay

Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay

eIF4G is required for the pioneer round of translation in mammalian cells

Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways

A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay

Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4)

Novel Upf2p orthologues suggest a functional link between translation initiation and nonsense surveillance complexes

P304

e92

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1371/JOURNAL.PBIO.0060092

http://www.w3.org/2001/XMLSchema#string

P407

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

6

http://www.w3.org/2001/XMLSchema#string

P50

Oliver Mühlemann

P577

2008-04-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

5404055

http://www.w3.org/2001/XMLSchema#string

P698

18447580

http://www.w3.org/2001/XMLSchema#string

P932

2689704

http://www.w3.org/2001/XMLSchema#string