Loss of cks1 homeostasis deregulates cell division cycle. - sprookjes - yvandenbroek - TriplyDB

Loss of cks1 homeostasis deregulates cell division cycle.

Loss of cks1 homeostasis deregulates cell division cycle.

http://www.wikidata.org/entity/Q37334970

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Chronic occupational exposure to arsenic induces carcinogenic gene signaling networks and neoplastic transformation in human lung epithelial cells Tampering with cell division by using small-molecule inhibitors of CDK-CKS protein interactions.TGF-β activates APC through Cdh1 binding for Cks1 and Skp2 proteasomal destruction stabilizing p27kip1 for normal endometrial growth.Increased expression of Cks1 protein is associated with lymph node metastasis and poor prognosis in nasopharyngeal carcinoma.Cks1: Structure, Emerging Roles and Implications in Multiple Cancers Flipping the switch from g1 to s phase with e3 ubiquitin ligases NEDD8 Inhibition Overcomes CKS1B-Induced Drug Resistance by Upregulation of p21 in Multiple Myeloma.Cancer specificity of promoters of the genes controlling cell proliferation.Cancer specificity of promoters of the genes involved in cell proliferation control Clinicopathological characteristics and genomic profile of primary sinonasal tract diffuse large B cell lymphoma (DLBCL) reveals gain at 1q31 and RGS1 encoding protein; high RGS1 immunohistochemical expression associates with poor overall survival i Cyclin-dependent kinase inhibitor flavopiridol promotes remyelination in a cuprizone induced demyelination model.Gene expression profiling identifies different sub-types of retinoblastoma.The therapeutic potential of cell cycle targeting in multiple myeloma.Oncogenic Actions of SKP2 Involves Deregulation of CDK1 Turnover Mediated by FOXM1.Cell adhesion is regulated by CDK1 during the cell cycle

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Loss of cks1 homeostasis deregulates cell division cycle.

http://www.wikidata.org/entity/Q37334970

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 17 February 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Loss of cks1 homeostasis deregulates cell division cycle.

@en

Loss of cks1 homeostasis deregulates cell division cycle.

@nl

type

label

Loss of cks1 homeostasis deregulates cell division cycle.

@en

Loss of cks1 homeostasis deregulates cell division cycle.

@nl

prefLabel

Loss of cks1 homeostasis deregulates cell division cycle.

@en

Loss of cks1 homeostasis deregulates cell division cycle.

@nl

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J.1582-4934.2009.00698.X

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Journal of Cellular and Molecular Medicine

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Loss of cks1 homeostasis deregulates cell division cycle.

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Anand Krishnan

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M Radhakrishna Pillai

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S Asha Nair

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P2860

The expression of the ubiquitin ligase subunit Cks1 in human breast cancer

Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication

Human cDNAs encoding homologs of the small p34Cdc28/Cdc2-associated protein of Saccharomyces cerevisiae and Schizosaccharomyces pombe

A negatively charged amino acid in Skp2 is required for Skp2-Cks1 interaction and ubiquitination of p27Kip1

p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase

Crystal structure and mutational analysis of the human CDK2 kinase complex with cell cycle-regulatory protein CksHs1

Structural basis of the Cks1-dependent recognition of p27(Kip1) by the SCF(Skp2) ubiquitin ligase

Protein-protein interactions involved in the recognition of p27 by E3 ubiquitin ligase

p13suc1 acts in the fission yeast cell division cycle as a component of the p34cdc2 protein kinase

Role of Cks1 overexpression in oral squamous cell carcinomas: cooperation with Skp2 in promoting p27 degradation

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10.1111/J.1582-4934.2009.00698.X

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