The Tn antigen-structural simplicity and biological complexity. - sprookjes - yvandenbroek - TriplyDB

The Tn antigen-structural simplicity and biological complexity.

The Tn antigen-structural simplicity and biological complexity.

http://www.wikidata.org/entity/Q37831859

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ERK8 is a negative regulator of O-GalNAc glycosylation and cell migration Entirely Carbohydrate-Based Vaccines: An Emerging Field for Specific and Selective Immune Responses Regulation of the metastatic cell phenotype by sialylated glycans Glycotherapy: new advances inspire a reemergence of glycans in medicine Computational Screening of the Human TF-Glycome Provides a Structural Definition for the Specificity of Anti-Tumor Antibody JAA-F11 Deciphering Structural Elements of Mucin Glycoprotein Recognition Inflammation-Induced Adhesin-Receptor Interaction Provides a Fitness Advantage to Uropathogenic E. coli during Chronic Infection Platelet biogenesis and functions require correct protein O-glycosylation Winter Aconite (Eranthis hyemalis) Lectin as a cytotoxic effector in the lifecycle of Caenorhabditis elegans Deletion of atbf1/zfhx3 in mouse prostate causes neoplastic lesions, likely by attenuation of membrane and secretory proteins and multiple signaling pathways.MUC1 glycopeptide epitopes predicted by computational glycomics.Identification of distinct glycoforms of IgA1 in plasma from patients with immunoglobulin A (IgA) nephropathy and healthy individuals COSMC is overexpressed in proliferating infantile hemangioma and enhances endothelial cell growth via VEGFR2.Primary breast cancer tumours contain high amounts of IgA1 immunoglobulin: an immunohistochemical analysis of a possible carrier of the tumour-associated Tn antigen.Synthesis and biological evaluation of a novel MUC1 glycopeptide conjugate vaccine candidate comprising a 4'-deoxy-4'-fluoro-Thomsen-Friedenreich epitope.Single molecule study of heterotypic interactions between mucins possessing the Tn cancer antigen.Protein glycosylation in cancer.Cancer vaccines and carbohydrate epitopes.Aberrant Cosmc genes result in Tn antigen expression in human colorectal carcinoma cell line HT-29.Gap1 functions as a molecular chaperone to stabilize its interactive partner Gap3 during biogenesis of serine-rich repeat bacterial adhesin Promoters of Human Cosmc and T-synthase Genes Are Similar in Structure, Yet Different in Epigenetic Regulation Tight complex formation between Cosmc chaperone and its specific client non-native T-synthase leads to enzyme activity and client-driven dissociation.Synthetic Mucin-Like Glycopeptides as Versatile Tools to Measure Effects of Glycan Structure/Density/Position on the Interaction with Adhesion/Growth-Regulatory Galectins in Arrays.Density variant glycan microarray for evaluating cross-linking of mucin-like glycoconjugates by lectins.Pathobiological implications of mucin glycans in cancer: Sweet poison and novel targets.Evaluation of riproximin binding properties reveals a novel mechanism for cellular targeting Interactions between the breast cancer-associated MUC1 mucins and C-type lectin characterized by optical tweezers.Epigenetic silencing of the chaperone Cosmc in human leukocytes expressing tn antigen Significant Impact of Immunogen Design on the Diversity of Antibodies Generated by Carbohydrate-Based Anticancer Vaccine.Assessing breast cancer margins ex vivo using aqueous quantum-dot-molecular probes.Glycoprotein disease markers and single protein-omics Protein domain histochemistry (PDH): binding of the carbohydrate recognition domain (CRD) of recombinant human glycoreceptor CLEC10A (CD301) to formalin-fixed, paraffin-embedded breast cancer tissues Trimeric Tn antigen on syndecan 1 produced by ppGalNAc-T13 enhances cancer metastasis via a complex formation with integrin α5β1 and matrix metalloproteinase 9.Initiation of GalNAc-type O-glycosylation in the endoplasmic reticulum promotes cancer cell invasiveness.Golgb1 regulates protein glycosylation and is crucial for mammalian palate development Loss of N-acetylgalactosaminyltransferase 3 in poorly differentiated pancreatic cancer: augmented aggressiveness and aberrant ErbB family glycosylation.Effective antitumor therapy based on a novel antibody-drug conjugate targeting the Tn carbohydrate antigen The relation of the level of serum anti-TF, -Tn and -alpha-Gal IgG to survival in gastrointestinal cancer patients Microarray analysis of the human antibody response to synthetic Cryptosporidium glycopeptides.N-acetylgalactosaminyltransferases in cancer.

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The Tn antigen-structural simplicity and biological complexity.

http://www.wikidata.org/entity/Q37831859

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 21 January 2011

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

The Tn antigen-structural simplicity and biological complexity.

@en

The Tn antigen-structural simplicity and biological complexity.

@nl

type

label

The Tn antigen-structural simplicity and biological complexity.

@en

The Tn antigen-structural simplicity and biological complexity.

@nl

prefLabel

The Tn antigen-structural simplicity and biological complexity.

@en

The Tn antigen-structural simplicity and biological complexity.

@nl

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Angewandte Chemie International Edition

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The Tn antigen-structural simplicity and biological complexity.

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Richard D Cummings

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Tongzhong Ju

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Vivianne I Otto

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P2860

Molecular cloning and functional expression of two members of mouse NeuAcalpha2,3Galbeta1,3GalNAc GalNAcalpha2,6-sialyltransferase family, ST6GalNAc III and IV

Cloning and expression of a human gene encoding an N-acetylgalactosamine-alpha2,6-sialyltransferase (ST6GalNAc I): a candidate for synthesis of cancer-associated sialyl-Tn antigens

Cloning and expression of human core 1 beta1,3-galactosyltransferase

Molecular cloning and characterization of a novel UDP-GlcNAc:GalNAc-peptide beta1,3-N-acetylglucosaminyltransferase (beta 3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans

Variants of C1GALT1 gene are associated with the genetic susceptibility to IgA nephropathy

Dynamic association between the catalytic and lectin domains of human UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase-2

Expression cloning of a functional glycoprotein ligand for P-selectin

Episialin (MUC1) overexpression inhibits integrin-mediated cell adhesion to extracellular matrix components

The catalytic and lectin domains of UDP-GalNAc:polypeptide alpha-N-Acetylgalactosaminyltransferase function in concert to direct glycosylation site selection

A unique molecular chaperone Cosmc required for activity of the mammalian core 1 beta 3-galactosyltransferase

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1770-1791

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scholarly article

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10.1002/ANIE.201002313

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8

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50

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2011-01-21T00:00:00Z

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49778491

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21259410

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