Review of poly (ADP-ribose) polymerase (PARP) mechanisms of action and rationale for targeting in cancer and other diseases.
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Tetra-O-Methyl Nordihydroguaiaretic Acid Broadly Suppresses Cancer Metabolism and Synergistically Induces Strong Anticancer Activity in Combination with Etoposide, Rapamycin and UCN-01Kynurenine Pathway of Tryptophan Metabolism: Regulatory and Functional Aspects.NAD+ augmentation ameliorates acute pancreatitis through regulation of inflammasome signalling.Combination Platinum-based and DNA Damage Response-targeting Cancer Therapy: Evolution and Future Directions.Effect of adriamycin on BRCA1 and PARP-1 expression in MCF-7 breast cancer cells.DNA damage response markers are differentially expressed in BRCA-mutated breast cancersGeneration of an algorithm based on minimal gene sets to clinically subtype triple negative breast cancer patients.PARP Inhibitor PJ34 Suppresses Osteogenic Differentiation in Mouse Mesenchymal Stem Cells by Modulating BMP-2 Signaling PathwayNovel PARP-1 Inhibitor Scaffolds Disclosed by a Dynamic Structure-Based Pharmacophore Approach.Induction of Poly(ADP-ribose) Polymerase in Mouse Bone Marrow Stromal Cells Exposed to 900 MHz Radiofrequency Fields: Preliminary Observations.NAD+ Supplementation Attenuates Methylmercury Dopaminergic and Mitochondrial Toxicity in Caenorhabditis Elegans.Reverse the Resistance to PARP Inhibitors.HM015k, a Novel Silybin Derivative, Multi-Targets Metastatic Ovarian Cancer Cells and Is Safe in Zebrafish Toxicity StudiesA Study on the Anticarcinogenic Effects of Calcium Fructoborate.Insight into the machinery that oils chromatin dynamics.The PARP family: insights into functional aspects of poly (ADP-ribose) polymerase-1 in cell growth and survival.Kynurenine pathway metabolism and neuroinflammatory disease.Benzimidazole Scaffold as Anticancer Agent: Synthetic Approaches and Structure-Activity Relationship.Poly (ADP-Ribose) Polymerase-1 (PARP-1) Induction by Cocaine Is Post-Transcriptionally Regulated by miR-125b.Inhibitory effect of black tea pigments, theaflavin‑3/3'-gallate against cisplatin-resistant ovarian cancer cells by inducing apoptosis and G1 cell cycle arrest.Anticancer effect of dentatin and dentatin-hydroxypropyl-β-cyclodextrin complex on human colon cancer (HT-29) cell line.Anti-apoptotic effect of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) polymerase, against multiple organ damage induced by gamma irradiation in rats.Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression.Cancer: Towards a general theory of the target: All successful cancer therapies, actual or potential, are reducible to either (or both) of two fundamental strategies.Automodification of PARP and fatty acid-based membrane lipidome as a promising integrated biomarker panel in molecular medicine.NAD + biosynthesis, aging, and disease.Role of IGF-1R in ameliorating apoptosis of GNE deficient cells.Aberrations of DNA Repair Pathways in Prostate Cancer: Future Implications for Clinical Practice?Response to olaparib in metastatic castration-resistant prostate cancer with germline BRCA2 mutation: a case reportPoly(ADP-ribose) polymerase 1 searches DNA via a 'monkey bar' mechanism
P2860
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P2860
Review of poly (ADP-ribose) polymerase (PARP) mechanisms of action and rationale for targeting in cancer and other diseases.
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article científic
@ca
article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
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artículo científico
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name
Review of poly (ADP-ribose) po ...... in cancer and other diseases.
@en
type
label
Review of poly (ADP-ribose) po ...... in cancer and other diseases.
@en
prefLabel
Review of poly (ADP-ribose) po ...... in cancer and other diseases.
@en
P2093
P2860
P1476
Review of poly (ADP-ribose) po ...... g in cancer and other diseases
@en
P2093
David A Boothman
Erik A Bey
Farjana J Fattah
Jinming Gao
Longshan Li
Malina Patel
P2860
P356
10.1615/CRITREVEUKARYOTGENEEXPR.2013006875
P577
2014-01-01T00:00:00Z