Asxl1 deficiency in embryonic fibroblasts leads to cellular senescence via impairment of the AKT-E2F pathway and Ezh2 inactivation.

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Asxl1 exerts an antiproliferative effect on mouse lung maturation via epigenetic repression of the E2f1-Nmyc axis

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Asxl1 deficiency in embryonic fibroblasts leads to cellular senescence via impairment of the AKT-E2F pathway and Ezh2 inactivation.

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2017 nî lūn-bûn

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2017年の論文

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2017年論文

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2017年论文

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Asxl1 deficiency in embryonic ...... pathway and Ezh2 inactivation.

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Asxl1 deficiency in embryonic ...... pathway and Ezh2 inactivation.

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Asxl1 deficiency in embryonic ...... pathway and Ezh2 inactivation.

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P1476

Asxl1 deficiency in embryonic ...... pathway and Ezh2 inactivation.

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Eun-Joo Kim

http://www.w3.org/2001/XMLSchema#string

Hye Sook Youn

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Jin-Taek Hwang

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Seung-Tae Moon

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So-Jung An

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Soo-Jong Um

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Tae-Yoon Kim

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Ui-Hyun Park

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Yong-Kyu Lee

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ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression

Additional sex comb-like (ASXL) proteins 1 and 2 play opposite roles in adipogenesis via reciprocal regulation of peroxisome proliferator-activated receptor {gamma}

Mechanism of activation of protein kinase B by insulin and IGF-1

Protein interaction data set highlighted with human Ras-MAPK/PI3K signaling pathways

Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA

Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma

AKT/PKB signaling: navigating downstream

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

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s41598-017-05564-x

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scholarly article

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10.1038/S41598-017-05564-X

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English

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2017-07-12T00:00:00Z

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1090546664

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Asxl1 deficiency in embryonic fibroblasts leads to cellular senescence via impairment of the AKT-E2F pathway and Ezh2 inactivation.

about

P2860

P2860

Asxl1 deficiency in embryonic fibroblasts leads to cellular senescence via impairment of the AKT-E2F pathway and Ezh2 inactivation.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P433

P478

P577

P6179

P698

P932

P356

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P433

P478

P577

P6179

P698

P932