Incorporation of fluorotyrosines into ribonucleotide reductase using an evolved, polyspecific aminoacyl-tRNA synthetase.
about
A genetically encoded 19F NMR probe for tyrosine phosphorylationAt the Interface of Chemical and Biological Synthesis: An Expanded Genetic Code.Direct Interfacial Y731 Oxidation in α2 by a Photoβ2 Subunit of E. coli Class Ia Ribonucleotide Reductase.Mechanism of the AppABLUF Photocycle Probed by Site-Specific Incorporation of Fluorotyrosine Residues: Effect of the Y21 pKa on the Forward and Reverse Ground-State ReactionsGenetically encoded fluorophenylalanines enable insights into the recognition of lysine trimethylation by an epigenetic reader.Defining the role of tyrosine and rational tuning of oxidase activity by genetic incorporation of unnatural tyrosine analogs.Generation of a stable, aminotyrosyl radical-induced α2β2 complex of Escherichia coli class Ia ribonucleotide reductase.Biophysical Characterization of Fluorotyrosine Probes Site-Specifically Incorporated into Enzymes: E. coli Ribonucleotide Reductase As an ExampleBiochemical analysis with the expanded genetic lexicon.Understanding and applying tyrosine biochemical diversity.Fluoro amino acids: a rarity in nature, yet a prospect for protein engineering.Biocatalysis with Unnatural Amino Acids: Enzymology Meets Xenobiology.Reverse Electron Transfer Completes the Catalytic Cycle in a 2,3,5-Trifluorotyrosine-Substituted Ribonucleotide Reductase.A >200 meV Uphill Thermodynamic Landscape for Radical Transport in Escherichia coli Ribonucleotide Reductase Determined Using Fluorotyrosine-Substituted Enzymes.Formal reduction potential of 3,5-difluorotyrosine in a structured protein: insight into multistep radical transfer.Modulation of Y356 photooxidation in E. coli class Ia ribonucleotide reductase by Y731 across the α2:β2 interface.Kinetics of hydrogen atom abstraction from substrate by an active site thiyl radical in ribonucleotide reductaseElectron hopping through proteins.Charge-Transfer Dynamics at the α/β Subunit Interface of a Photochemical Ribonucleotide Reductase.Reversible, long-range radical transfer in E. coli class Ia ribonucleotide reductase.Glutamate 350 Plays an Essential Role in Conformational Gating of Long-Range Radical Transport in Escherichia coli Class Ia Ribonucleotide Reductase.Photoactivation of the BLUF Protein PixD Probed by the Site-Specific Incorporation of Fluorotyrosine Residues.Fluorescence Modulation of Green Fluorescent Protein Using Fluorinated Unnatural Amino Acids.Formal Reduction Potentials of Difluorotyrosine and Trifluorotyrosine Protein Residues: Defining the Thermodynamics of Multistep Radical Transfer.Playing with the molecules of life.Glutamate 52-β at the α/β subunit interface of Escherichia coli class Ia ribonucleotide reductase is essential for conformational gating of radical transfer.Properties of Site-Specifically Incorporated 3-Aminotyrosine in Proteins To Study Redox-Active Tyrosines: Escherichia coli Ribonucleotide Reductase as a Paradigm.Modulating the pKa of a tyrosine in KlenTaq DNA polymerase that is crucial for abasic site bypass by in vivo incorporation of a non-canonical amino acid.Photochemical Rescue of a Conformationally Inactivated Ribonucleotide ReductaseCleavage of a carbon-fluorine bond by an engineered cysteine dioxygenaseBiosynthetic approach to modeling and understanding metalloproteins using unnatural amino acids
P2860
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P2860
Incorporation of fluorotyrosines into ribonucleotide reductase using an evolved, polyspecific aminoacyl-tRNA synthetase.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Incorporation of fluorotyrosin ...... fic aminoacyl-tRNA synthetase.
@en
type
label
Incorporation of fluorotyrosin ...... fic aminoacyl-tRNA synthetase.
@en
prefLabel
Incorporation of fluorotyrosin ...... fic aminoacyl-tRNA synthetase.
@en
P2093
P2860
P356
P1476
Incorporation of fluorotyrosin ...... fic aminoacyl-tRNA synthetase.
@en
P2093
Douglas D Young
Ellen C Minnihan
Peter G Schultz
P2860
P304
15942-15945
P356
10.1021/JA207719F
P407
P577
2011-09-21T00:00:00Z