A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors. - sprookjes - yvandenbroek - TriplyDB

A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors.

A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors.

http://www.wikidata.org/entity/Q38905550

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Regulatory mechanisms of microRNAs in lung cancer stem cells NOTCH receptors in gastric and other gastrointestinal cancers: oncogenes or tumor suppressors?EMT, CTCs and CSCs in tumor relapse and drug-resistance Notch1 is a 5-fluorouracil resistant and poor survival marker in human esophagus squamous cell carcinomas Control by a hair's breadth: the role of microRNAs in the skin Esophageal epithelial cells acquire functional characteristics of activated myofibroblasts after undergoing an epithelial to mesenchymal transition.Identifying global expression patterns and key regulators in epithelial to mesenchymal transition through multi-study integration.Functional analysis of the mRNA profile of neutrophil gelatinase‑associated lipocalin overexpression in esophageal squamous cell carcinoma using multiple bioinformatic tools.Tumor suppressive microRNA-1285 regulates novel molecular targets: aberrant expression and functional significance in renal cell carcinoma.Targeting the PDGF signaling pathway in tumor treatment Concerted loss of TGFβ-mediated proliferation control and E-cadherin disrupts epithelial homeostasis and causes oral squamous cell carcinoma.Meta-analysis of gene expression signatures defining the epithelial to mesenchymal transition during cancer progression MCRS1 overexpression, which is specifically inhibited by miR-129*, promotes the epithelial-mesenchymal transition and metastasis in non-small cell lung cancer.miR-29a activates Hes1 by targeting Nfia in esophageal carcinoma cell line TE-1 Epithelial-mesenchymal transition spectrum quantification and its efficacy in deciphering survival and drug responses of cancer patients.Global changes in gene expression of Barrett's esophagus compared to normal squamous esophagus and gastric cardia tissues.Preclinical validation of talaporfin sodium-mediated photodynamic therapy for esophageal squamous cell carcinoma.Concise review: custodians of the transcriptome: how microRNAs guard stemness in squamous epithelia.Interleukin-17-induced EMT promotes lung cancer cell migration and invasion via NF-κB/ZEB1 signal pathway Hypoxia induces IGFBP3 in esophageal squamous cancer cells through HIF-1α-mediated mRNA transcription and continuous protein synthesis Novel 5-fluorouracil-resistant human esophageal squamous cell carcinoma cells with dihydropyrimidine dehydrogenase overexpression.Comparative genomic analysis of esophageal adenocarcinoma and squamous cell carcinoma.Noncoding RNA Expression Aberration Is Associated with Cancer Progression and Is a Potential Biomarker in Esophageal Squamous Cell Carcinoma.Correlation between microRNA-421 expression level and prognosis of gastric cancer Molecular mechanisms of ethanol-associated oro-esophageal squamous cell carcinoma.MicroRNA-421 Gene Polymorphism in Gastric Carcinoma.IGFBP3 promotes esophageal cancer growth by suppressing oxidative stress in hypoxic tumor microenvironment Na+/H+ exchanger 1 has tumor suppressive activity and prognostic value in esophageal squamous cell carcinoma.EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness.Stem-like cells and therapy resistance in squamous cell carcinomas The Secret Role of microRNAs in Cancer Stem Cell Development and Potential Therapy: A Notch-Pathway Approach Genomic and Epigenomic Aberrations in Esophageal Squamous Cell Carcinoma and Implications for Patients.Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance.A pivotal role of Krüppel-like factor 5 in regulation of cancer stem-like cells in hepatocellular carcinoma.EGFR inhibitors prevent induction of cancer stem-like cells in esophageal squamous cell carcinoma by suppressing epithelial-mesenchymal transition.Mitochondrial SOD2 regulates epithelial-mesenchymal transition and cell populations defined by differential CD44 expression.EGFR inhibition promotes an aggressive invasion pattern mediated by mesenchymal-like tumor cells within squamous cell carcinomas Aberrant expression of microRNAs involved in epithelial-mesenchymal transition of HT-29 cell line.Distinct effects of EGFR inhibitors on epithelial- and mesenchymal-like esophageal squamous cell carcinoma cells.Autophagy mediates epithelial cytoprotection in eosinophilic oesophagitis.

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A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors.

http://www.wikidata.org/entity/Q38905550

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年學術文章

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2011年學術文章

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2011年學術文章

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name

A NOTCH3-mediated squamous cel ...... the ZEB transcription factors.

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type

label

A NOTCH3-mediated squamous cel ...... the ZEB transcription factors.

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prefLabel

A NOTCH3-mediated squamous cel ...... the ZEB transcription factors.

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0008-5472.CAN-11-0846

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Cancer Research

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A NOTCH3-mediated squamous cel ...... the ZEB transcription factors

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Andres J Klein-Szanto

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Devraj Basu

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Hiroshi Itoh

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Hiroshi Nakagawa

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J Alan Diehl

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Meenhard Herlyn

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Momo Nakagawa

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Phyllis A Gimotty

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Ross A Kalman

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Seiji Naganuma

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P2860

Induction of EMT by twist proteins as a collateral effect of tumor-promoting inactivation of premature senescence

Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling

The ZEB/miR-200 feedback loop--a motor of cellular plasticity in development and cancer?

The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression

The epithelial-mesenchymal transition generates cells with properties of stem cells

The basics of epithelial-mesenchymal transition

Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinases

Epithelial-mesenchymal transitions in development and disease

Slug Expression in the E-cadherin preserved tumors is related to prognosis in patients with esophageal squamous cell carcinoma

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6836-6847

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10.1158/0008-5472.CAN-11-0846

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21

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71

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Douglas S Darling

Mitsuteru Natsuizaka

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2011-09-02T00:00:00Z

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51618072

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21890822

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3206139

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