DNA replication timing and higher-order nuclear organization determine single-nucleotide substitution patterns in cancer genomes.
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Complex correlations: replication timing and mutational landscapes during cancer and genome evolutionCoordination of DNA damage tolerance mechanisms with cell cycle progression in fission yeast.Hypermutation in human cancer genomes: footprints and mechanismsAn Evolutionary Approach for Identifying Driver Mutations in Colorectal CancerThe mutation spectrum in genomic late replication domains shapes mammalian GC contentA Simple Model-Based Approach to Inferring and Visualizing Cancer Mutation Signatures.Handling realistic assumptions in hypothesis testing of 3D co-localization of genomic elements.A computational strategy to adjust for copy number in tumor Hi-C data.A new light on DNA replication from the inactive X chromosomeChromatin structure and replication origins: determinants of chromosome replication and nuclear organizationTranscription restores DNA repair to heterochromatin, determining regional mutation rates in cancer genomes.Cell-of-origin chromatin organization shapes the mutational landscape of cancerIncreasing Nucleosome Occupancy Is Correlated with an Increasing Mutation Rate so Long as DNA Repair Machinery Is Intact.Signatures of accelerated somatic evolution in gene promoters in multiple cancer types.The effects of chromatin organization on variation in mutation rates in the genome.Genome-wide Determination of Mammalian Replication Timing by DNA Content Measurement.APOBEC-Induced Cancer Mutations Are Uniquely Enriched in Early-Replicating, Gene-Dense, and Active Chromatin RegionsGenomic approaches to DNA repair and mutagenesis.Mutation pattern is an influential factor on functional mutation rates in cancer.Coevolution between Nuclear-Encoded DNA Replication, Recombination, and Repair Genes and Plastid Genome Complexity.Next-generation sequencing of paired tyrosine kinase inhibitor-sensitive and -resistant EGFR mutant lung cancer cell lines identifies spectrum of DNA changes associated with drug resistanceLoss of heterozygosity preferentially occurs in early replicating regions in cancer genomes.The topography of mutational processes in breast cancer genomes.Are sites with multiple single nucleotide variants in cancer genomes a consequence of drivers, hypermutable sites or sequencing errors?Hypermutation of the inactive X chromosome is a frequent event in cancer.Mechanisms of base substitution mutagenesis in cancer genomes.OncodriveCLUST: exploiting the positional clustering of somatic mutations to identify cancer genes.Beyond the exome: the role of non-coding somatic mutations in cancer.An epigenetic gateway to brain tumor cell identity.From Mutational Mechanisms in Single Cells to Mutational Patterns in Cancer Genomes.Analysis of a transgenic Oct4 enhancer reveals high fidelity long-range chromosomal interactions.Sources and consequences of oxidative damage from mitochondria and neurotransmitter signaling.Differential DNA mismatch repair underlies mutation rate variation across the human genome.UV-Induced DNA Damage and Mutagenesis in Chromatin.Perturbations in the Replication Program Contribute to Genomic Instability in Cancer.Spatially coordinated replication and minimization of expression noise constrain three-dimensional organization of yeast genome.Analysis of replication timing using synchronized budding yeast cultures.The distribution of genomic variations in human iPSCs is related to replication-timing reorganization during reprogramming.The 3DGD: a database of genome 3D structure.Chromatin marks shape mutation landscape at early stage of cancer progression.
P2860
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P2860
DNA replication timing and higher-order nuclear organization determine single-nucleotide substitution patterns in cancer genomes.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
DNA replication timing and hig ...... on patterns in cancer genomes.
@en
type
label
DNA replication timing and hig ...... on patterns in cancer genomes.
@en
prefLabel
DNA replication timing and hig ...... on patterns in cancer genomes.
@en
P2093
P2860
P356
P1476
DNA replication timing and hig ...... on patterns in cancer genomes.
@en
P2093
Franziska Michor
Subhajyoti De
P2860
P2888
P356
10.1038/NCOMMS2502
P407
P577
2013-01-01T00:00:00Z