Dual roles for the phosphatase PPM1D in regulating progesterone receptor function. - sprookjes - yvandenbroek - TriplyDB

Dual roles for the phosphatase PPM1D in regulating progesterone receptor function.

Dual roles for the phosphatase PPM1D in regulating progesterone receptor function.

http://www.wikidata.org/entity/Q40340400

about

A chemical inhibitor of PPM1D that selectively kills cells overexpressing PPM1D.Integrative genome-wide expression analysis bears evidence of estrogen receptor-independent transcription in heregulin-stimulated MCF-7 cells.Progesterone action in human tissues: regulation by progesterone receptor (PR) isoform expression, nuclear positioning and coregulator expression.Kinases and protein phosphorylation as regulators of steroid hormone action Genetic characterization of breast cancer and implications for clinical management Inhibition of p38-MAPK alters SRC coactivation and estrogen receptor phosphorylation.Regulation of the Wip1 phosphatase and its effects on the stress response.The type 2C phosphatase Wip1: an oncogenic regulator of tumor suppressor and DNA damage response pathways.In utero exposure to low doses of environmental pollutants disrupts fetal ovarian development in sheep.Hormone-sensing cells require Wip1 for paracrine stimulation in normal and premalignant mammary epithelium Nuclear receptor coregulators in cancer biology.Stress induced gene expression: a direct role for MAPKAP kinases in transcriptional activation of immediate early genes.Estradiol up-regulates AUF1p45 binding to stabilizing regions within the 3'-untranslated region of estrogen receptor alpha mRNA.

P2860

Q33294239-AFBBF73C-9B5F-4DE2-9C7E-F4ED58650E5D Q33324386-626C53DA-C149-43AE-B4A1-7D2139C7FFA0 Q33595229-4AC89EF7-DDE0-4C78-BE04-311F2A939E82 Q35809009-010E754B-A0DB-4314-867A-2A9263B118EA Q35832016-16C9CD6E-EFF1-481C-ACC2-EAE658B6A330 Q36289883-FCDBC27D-C393-4DEA-8FA8-7BACD27C6876 Q36429982-33A69CFE-FA62-4079-A08F-E2665E91BC0A Q36617172-C25BF73E-745B-45C4-A742-58799CDC9AB0 Q36692536-EDC717CC-191F-4DDD-99C7-883E8C67F553 Q36903215-6BFF40F5-4C7D-4421-8571-FC0755E2448D Q37618468-BA803DA4-7D90-4589-AF6C-4B2A3D6D6468 Q41820861-D121A2C5-7758-48D1-ACFA-23E8583D2D14 Q46888895-D709147D-526C-4362-BB17-5AB1916B4DC4

P2860

Dual roles for the phosphatase PPM1D in regulating progesterone receptor function.

http://www.wikidata.org/entity/Q40340400

description

2005 nî lūn-bûn

@nan

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

2005年论文

@zh

2005年论文

@zh-cn

name

Dual roles for the phosphatase PPM1D in regulating progesterone receptor function.

@en

type

label

Dual roles for the phosphatase PPM1D in regulating progesterone receptor function.

@en

prefLabel

Dual roles for the phosphatase PPM1D in regulating progesterone receptor function.

@en

P1433

Q40340400-F95A029B-EAF3-41BE-BCC7-E0E31140E9FD

P1476

Q40340400-B8123E84-96B5-456F-82F4-43E624D8261C

P2093

Q40340400-0BC4DBDA-B06F-4008-B05F-BD808621DCD8

Q40340400-20570CE5-EA22-4B8F-89EC-D18C1AFDA23A

Q40340400-D67CD785-C22D-45AF-94E4-58CB6A6F25DE

Q40340400-F4C956F7-90BE-48E2-8487-555DB7D633AC

P2860

Q40340400-02376C07-99AB-4352-BCBA-32ACAB04B8D5

Q40340400-0C0E429B-B255-402B-95F1-10DBFC090FEC

Q40340400-0C936C69-1E84-4902-920A-C41720968DD1

Q40340400-1317E100-F780-4341-B882-5060AA0A5C3D

Q40340400-32AF773A-1D14-4B4D-BA6A-DF0E58C08292

Q40340400-366B8A0C-3226-4A49-8D34-367531BD297B

Q40340400-3DC08B92-F95E-4E51-8312-306202E2B424

Q40340400-3E3EEC63-DB4E-46FF-AC6B-47200B3F75C5

Q40340400-3FAD6D7C-F431-40D0-AA74-9F75B45CA5BC

Q40340400-4C25FA77-2036-40AD-9BF1-2D47264B7601

P304

Q40340400-DA03074F-0F1C-47CA-9EB9-62CC3EED3111

P31

Q40340400-E6E704E5-D967-49A5-A712-5414A4BDD66E

P356

Q40340400-0BAB3658-E391-4EC6-B720-8346EF256693

P407

Q40340400-0803B93E-48E2-40B1-8E83-6045CE206DC5

P433

Q40340400-27C373BE-AE88-4A32-9973-6A11B0F37F58

P478

Q40340400-48357D78-F28E-4787-95DD-6DFA2BA643E7

P577

Q40340400-F4E02D4E-4D69-4C3C-B3D0-43B7C33FC6B1

P5875

Q40340400-B1DA95C9-7F97-426A-8C9A-8AA278BFED49

P698

Q40340400-52F70F18-B07D-4423-B218-3DED8B68E124

P356

P1433

Journal of Biological Chemistry

P1476

Dual roles for the phosphatase PPM1D in regulating progesterone receptor function.

@en

P2093

Bonnie W Nannenga

http://www.w3.org/2001/XMLSchema#string

David A Proia

http://www.w3.org/2001/XMLSchema#string

Lawrence A Donehower

http://www.w3.org/2001/XMLSchema#string

Nancy L Weigel

http://www.w3.org/2001/XMLSchema#string

P2860

Repressors of androgen and progesterone receptor action

Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner

PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints

Mice deficient for the wild-type p53-induced phosphatase gene (Wip1) exhibit defects in reproductive organs, immune function, and cell cycle control

Cdc25B functions as a novel coactivator for the steroid receptors

p53-inducible wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation

Activation of estrogen receptor alpha by S118 phosphorylation involves a ligand-dependent interaction with TFIIH and participation of CDK7

Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase

Minireview: nuclear receptor coactivators--an update

Oncogenic properties of PPM1D located within a breast cancer amplification epicenter at 17q23

P304

7089-7101

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M511839200

http://www.w3.org/2001/XMLSchema#string

P407

P433

11

http://www.w3.org/2001/XMLSchema#string

P478

281

http://www.w3.org/2001/XMLSchema#string

P577

2005-12-13T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

7416630

http://www.w3.org/2001/XMLSchema#string

P698

16352595

http://www.w3.org/2001/XMLSchema#string