Probing dynamics of HIV-1 nucleocapsid protein/target hexanucleotide complexes by 2-aminopurine
about
Structural insights into the cTAR DNA recognition by the HIV-1 nucleocapsid protein: role of sugar deoxyriboses in the binding polarity of NCDynamics of linker residues modulate the nucleic acid binding properties of the HIV-1 nucleocapsid protein zinc fingersIntrinsic nucleic acid dynamics modulates HIV-1 nucleocapsid protein binding to its targets.Conquering 2-aminopurine's deficiencies: highly emissive isomorphic guanosine surrogate faithfully monitors guanosine conformation and dynamics in DNAA phenyl-thiadiazolylidene-amine derivative ejects zinc from retroviral nucleocapsid zinc fingers and inactivates HIV virions.Molecular determinants of HIV-1 NCp7 chaperone activity in maturation of the HIV-1 dimerization initiation site.Site-selective probing of cTAR destabilization highlights the necessary plasticity of the HIV-1 nucleocapsid protein to chaperone the first strand transfer.Quantitative sampling of conformational heterogeneity of a DNA hairpin using molecular dynamics simulations and ultrafast fluorescence spectroscopyAromatic residue mutations reveal direct correlation between HIV-1 nucleocapsid protein's nucleic acid chaperone activity and retroviral replicationDissecting structural transitions in the HIV-1 dimerization initiation site RNA using 2-aminopurine fluorescence.The N-terminal zinc finger and flanking basic domains represent the minimal region of the human immunodeficiency virus type-1 nucleocapsid protein for targeting chaperone function.Characterization of the inhibition mechanism of HIV-1 nucleocapsid protein chaperone activities by methylated oligoribonucleotides.Specific implications of the HIV-1 nucleocapsid zinc fingers in the annealing of the primer binding site complementary sequences during the obligatory plus strand transfer.Sensing peptide-oligonucleotide interactions by a two-color fluorescence label: application to the HIV-1 nucleocapsid protein.A DFT study of 2-aminopurine-containing dinucleotides: prediction of stacked conformations with B-DNA structure.Pirenzepine promotes the dimerization of muscarinic M1 receptors through a three-step binding process.Analysis of the RNA chaperoning activity of the hepatitis C virus core protein on the conserved 3'X region of the viral genome.Design, synthesis and biological evaluation of TAR and cTAR binders as HIV-1 nucleocapsid inhibitors
P2860
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P2860
Probing dynamics of HIV-1 nucleocapsid protein/target hexanucleotide complexes by 2-aminopurine
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Probing dynamics of HIV-1 nucl ...... ide complexes by 2-aminopurine
@en
Probing dynamics of HIV-1 nucl ...... ide complexes by 2-aminopurine
@nl
type
label
Probing dynamics of HIV-1 nucl ...... ide complexes by 2-aminopurine
@en
Probing dynamics of HIV-1 nucl ...... ide complexes by 2-aminopurine
@nl
prefLabel
Probing dynamics of HIV-1 nucl ...... ide complexes by 2-aminopurine
@en
Probing dynamics of HIV-1 nucl ...... ide complexes by 2-aminopurine
@nl
P2093
P2860
P356
P1476
Probing dynamics of HIV-1 nucl ...... ide complexes by 2-aminopurine
@en
P2093
H de Rocquigny
S V Avilov
P2860
P304
P356
10.1093/NAR/GKM1109
P577
2007-12-17T00:00:00Z