Multiple functional domains of human U2 small nuclear RNA: strengthening conserved stem I can block splicing
about
Combined biochemical and electron microscopic analyses reveal the architecture of the mammalian U2 snRNPStructure and thermodynamics of a conserved U2 snRNA domain from yeast and humanThe DExD/H-box ATPase Prp2p destabilizes and proofreads the catalytic RNA core of the spliceosome.Functionally important structural elements of U12 snRNAA base-pairing interaction between U2 and U6 small nuclear RNAs occurs in > 150S complexes in HeLa cell extracts: implications for the spliceosome assembly pathway.Invariant U2 RNA sequences bordering the branchpoint recognition region are essential for interaction with yeast SF3a and SF3b subunits.Free energy landscapes of RNA/RNA complexes: with applications to snRNA complexes in spliceosomes.Multiple functions for the invariant AGC triad of U6 snRNA.The phylogenetically invariant ACAGAGA and AGC sequences of U6 small nuclear RNA are more tolerant of mutation in human cells than in Saccharomyces cerevisiaeU2 snRNA-protein contacts in purified human 17S U2 snRNPs and in spliceosomal A and B complexes.An mRNA-type intron is present in the Rhodotorula hasegawae U2 small nuclear RNA gene.
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Multiple functional domains of human U2 small nuclear RNA: strengthening conserved stem I can block splicing
description
1992 nî lūn-bûn
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1992年の論文
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1992年学术文章
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Multiple functional domains of ...... rved stem I can block splicing
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Multiple functional domains of ...... rved stem I can block splicing
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Multiple functional domains of ...... rved stem I can block splicing
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Multiple functional domains of ...... rved stem I can block splicing
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Multiple functional domains of ...... rved stem I can block splicing
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Multiple functional domains of ...... rved stem I can block splicing
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P2860
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Multiple functional domains of ...... rved stem I can block splicing
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10.1128/MCB.12.12.5464
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1992-12-01T00:00:00Z