Spatial control of the GEN1 Holliday junction resolvase ensures genome stability.
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Maintaining Genome Stability in Defiance of Mitotic DNA DamageHold your horSSEs: controlling structure-selective endonucleases MUS81 and Yen1/GEN1Regulation of Mutagenic DNA Polymerase V Activation in Space and TimeNucleo-cytoplasmic shuttling of the endonuclease ankyrin repeats and LEM domain-containing protein 1 (Ankle1) is mediated by canonical nuclear export- and nuclear import signalsSubstrate preference of Gen endonucleases highlights the importance of branched structures as DNA damage repair intermediates.Kinase-dead ATM protein is highly oncogenic and can be preferentially targeted by Topo-isomerase I inhibitorsReplication intermediates that escape Dna2 activity are processed by Holliday junction resolvase Yen1.Resolution of single and double Holliday junction recombination intermediates by GEN1.Endonuclease EEPD1 Is a Gatekeeper for Repair of Stressed Replication ForksResolution of Recombination Intermediates: Mechanisms and Regulation.An Overview of the Molecular Mechanisms of Recombinational DNA Repair.TopBP1-mediated DNA processing during mitosis.Holliday junction-resolving enzymes-structures and mechanisms.The control of DNA repair by the cell cycle.Cell cycle-dependent control of homologous recombination.Structural and Mechanistic Analysis of the Slx1-Slx4 EndonucleaseSLX4 Prevents GEN1-Dependent DSBs During DNA Replication Arrest Under Pathological Conditions in Human Cells.Human Holliday junction resolvase GEN1 uses a chromodomain for efficient DNA recognition and cleavage.The SMX DNA Repair Tri-nuclease.Genetic analysis of the Holliday junction resolvases Hje and Hjc in Sulfolobus islandicus.GEN1 promotes Holliday junction resolution by a coordinated nick and counter-nick mechanism.Multi-invasions Are Recombination Byproducts that Induce Chromosomal Rearrangements.Unresolved recombination intermediates lead to ultra-fine anaphase bridges, chromosome breaks and aberrations.Resolvase OsGEN1 Mediates DNA Repair by Homologous Recombination.Main steps in DNA double-strand break repair: an introduction to homologous recombination and related processes.Disruption of Gen1 Causes Congenital Anomalies of the Kidney and Urinary Tract in Mice.The nucleolytic resolution of recombination intermediates in yeast mitotic cells.
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P2860
Spatial control of the GEN1 Holliday junction resolvase ensures genome stability.
description
2014 nî lūn-bûn
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2014年の論文
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2014年論文
@yue
2014年論文
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2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Spatial control of the GEN1 Holliday junction resolvase ensures genome stability.
@en
Spatial control of the GEN1 Holliday junction resolvase ensures genome stability.
@nl
type
label
Spatial control of the GEN1 Holliday junction resolvase ensures genome stability.
@en
Spatial control of the GEN1 Holliday junction resolvase ensures genome stability.
@nl
prefLabel
Spatial control of the GEN1 Holliday junction resolvase ensures genome stability.
@en
Spatial control of the GEN1 Holliday junction resolvase ensures genome stability.
@nl
P2860
P356
P1476
Spatial control of the GEN1 Holliday junction resolvase ensures genome stability.
@en
P2860
P2888
P356
10.1038/NCOMMS5844
P407
P577
2014-09-11T00:00:00Z