about
The emerging role of peptidyl-prolyl isomerase chaperones in tau oligomerization, amyloid processing, and Alzheimer's diseaseRhodacyanine derivative selectively targets cancer cells and overcomes tamoxifen resistanceFacilitating Akt clearance via manipulation of Hsp70 activity and levels.The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules.Hsc70 rapidly engages tau after microtubule destabilizationAge-associated epigenetic upregulation of the FKBP5 gene selectively impairs stress resiliency.LPS- induced inflammation exacerbates phospho-tau pathology in rTg4510 miceEpitope analysis following active immunization with tau proteins reveals immunogens implicated in tau pathogenesis.Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice.Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathyTau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradationThe role of FKBP5 in mood disorders: action of FKBP5 on steroid hormone receptors leads to questions about its evolutionary importance.Potential synergy between tau aggregation inhibitors and tau chaperone modulators.Targeting Hsp90 and its co-chaperones to treat Alzheimer's diseaseHsp90 activator Aha1 drives production of pathological tau aggregates.DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative-associated proteins.MicroRNA-511 Binds to FKBP5 mRNA, Which Encodes a Chaperone Protein, and Regulates Neuronal Differentiation.Noncontact Rotational Head Injury Produces Transient Cognitive Deficits but Lasting Neuropathological Changes.Exploiting the diversity of the heat-shock protein family for primary and secondary tauopathy therapeutics.Isoform-selective Hsp90 inhibition rescues model of hereditary open-angle glaucoma.Imbalances in the Hsp90 Chaperone Machinery: Implications for Tauopathies.Trifunctional High-Throughput Screen Identifies Promising Scaffold To Inhibit Grp94 and Treat Myocilin-Associated Glaucoma.Hsp90 and FKBP51: complex regulators of psychiatric diseases.Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complexTargeting the FKBP51/GR/Hsp90 Complex to Identify Functionally Relevant Treatments for Depression and PTSDHsp90 Heterocomplexes Regulate Steroid Hormone Receptors: From Stress Response to Psychiatric DiseaseThe Disease-Associated Chaperone FKBP51 Impairs Cognitive Function by Accelerating AMPA Receptor RecyclingSmall Heat Shock Proteins, Big Impact on Protein Aggregation in Neurodegenerative DiseaseThe multiple facets of the Hsp90 machineRepeated repeat problems: Combinatorial effect of C9orf72-derived dipeptide repeat proteinsDynamic Aha1 co-chaperone binding to human Hsp90Early Life Stress and High FKBP5 Interact to Increase Anxiety-Like Symptoms through Altered AKT Signaling in the Dorsal HippocampusSpermidine/spermine-N1-acetyltransferase ablation impacts tauopathy-induced polyamine stress response
P50
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P50
description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Laura Blair
@ast
Laura Blair
@en
Laura Blair
@es
Laura Blair
@nl
Laura Blair
@sl
type
label
Laura Blair
@ast
Laura Blair
@en
Laura Blair
@es
Laura Blair
@nl
Laura Blair
@sl
prefLabel
Laura Blair
@ast
Laura Blair
@en
Laura Blair
@es
Laura Blair
@nl
Laura Blair
@sl
P106
P21
P2798
P31
P496
0000-0002-4981-5564