about
Genome and phylogenetic analyses of trypanosoma evansi reveal extensive similarity to T. brucei and multiple independent origins for dyskinetoplastyDifferences between Trypanosoma brucei gambiense groups 1 and 2 in their resistance to killing by trypanolytic factor 1The genetic map and comparative analysis with the physical map of Trypanosoma bruceiPopulation Genetics and Reproductive Strategies of African Trypanosomes: Revisiting Available Published DataTrypanosome resistance to human innate immunity: targeting Achilles' heelNovel African trypanocidal agents: membrane rigidifying peptidesDiscovery of mating in the major African livestock pathogen Trypanosoma congolenseA major genetic locus in Trypanosoma brucei is a determinant of host pathology.The genome sequence of Trypanosoma brucei gambiense, causative agent of chronic human african trypanosomiasisRole for parasite genetic diversity in differential host responses to Trypanosoma brucei infection.Digital gene expression analysis of two life cycle stages of the human-infective parasite, Trypanosoma brucei gambiense reveals differentially expressed clusters of co-regulated genes.Mechanism of Trypanosoma brucei gambiense (group 1) resistance to human trypanosome lytic factor.The skin is a significant but overlooked anatomical reservoir for vector-borne African trypanosomes.The TgsGP gene is essential for resistance to human serum in Trypanosoma brucei gambiense.Genetic analysis of phenotype in Trypanosoma brucei: a classical approach to potentially complex traits.The sequence and analysis of Trypanosoma brucei chromosome II.Exploiting genetic variation to discover genes involved in important disease phenotypes.Human African trypanosomiasis presenting at least 29 years after infection--what can this teach us about the pathogenesis and control of this neglected tropical disease?Population genomics reveals the origin and asexual evolution of human infective trypanosomes.Role of expression site switching in the development of resistance to human Trypanosome Lytic Factor-1 in Trypanosoma brucei bruceiA Primate APOL1 Variant That Kills Trypanosoma brucei gambiense.Use of multiple displacement amplification to increase the detection and genotyping of trypanosoma species samples immobilized on FTA filters.Genetic analysis of the human infective trypanosome Trypanosoma brucei gambiense: chromosomal segregation, crossing over, and the construction of a genetic mapWhole-genome sequencing of Trypanosoma brucei reveals introgression between subspecies that is associated with virulence.The population structure of the Cryptosporidium parvum population in Scotland: a complex picture.Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs.Candidate gene polymorphisms study between human African trypanosomiasis clinical phenotypes in Guinea.Population genetics of Trypanosoma brucei rhodesiense: clonality and diversity within and between foci.Population genetics of Trypanosoma brucei gambiense in sleeping sickness patients with treatment failures in the focus of Mbuji-Mayi, Democratic Republic of the Congo.The DNA sequence of chromosome I of an African trypanosome: gene content, chromosome organisation, recombination and polymorphism.Case of Nigeria-Acquired Human African Trypanosomiasis in United Kingdom, 2016.Multilocus genotyping of Cryptosporidium parvum Type 2: population genetics and sub-structuring.Population structures and the role of genetic exchange in the zoonotic pathogen Cryptosporidium parvum.A polymorphism in the haptoglobin, haptoglobin related protein locus is associated with risk of human sleeping sickness within Cameroonian populations.Candidate genes-based investigation of susceptibility to Human African Trypanosomiasis in Côte d'Ivoire.First evidence that parasite infecting apparent aparasitemic serological suspects in human African trypanosomiasis are Trypanosoma brucei gambiense and are similar to those found in patients.Trypanosoma vivax displays a clonal population structure.Trypanosoma brucei gambiense Type 1 populations from human patients are clonal and display geographical genetic differentiation.Allelic segregation and independent assortment in T. brucei crosses: proof that the genetic system is Mendelian and involves meiosis.Do Cryptic Reservoirs Threaten Gambiense-Sleeping Sickness Elimination?
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P50
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Annette MacLeod
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Annette MacLeod
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Annette MacLeod
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Annette MacLeod
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Annette MacLeod
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