about
Structural insight into the substrate specificity of DNA Polymerase muWerner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylationSibling rivalry: competition between Pol X family members in V(D)J recombination and general double strand break repairMechanism of suppression of chromosomal instability by DNA polymerase POLQBridging of double-stranded breaks by the nonhomologous end-joining ligation complex is modulated by DNA end chemistry.Nonhomologous end joining: a good solution for bad endsStructural insights into NHEJ: building up an integrated picture of the dynamic DSB repair super complex, one component and interaction at a timeCooperation of DNA-PKcs and WRN helicase in the maintenance of telomeric D-loopsRequirements for 5'dRP/AP lyase activity in Ku.Genomic instability due to V(D)J recombination-associated transposition.Werner protein cooperates with the XRCC4-DNA ligase IV complex in end-processingSensing of intermediates in V(D)J recombination by ATM.Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repairThe DNA-dependent protein kinase: the director at the end.Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and AktEssential role for polymerase specialization in cellular nonhomologous end joining.Nonhomologous end joining of complex DNA double-strand breaks with proximal thymine glycol and interplay with base excision repairReversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2A comparison of BRCT domains involved in nonhomologous end-joining: introducing the solution structure of the BRCT domain of polymerase lambda.Template strand scrunching during DNA gap repair synthesis by human polymerase lambda.Serines 440 and 467 in the Werner syndrome protein are phosphorylated by DNA-PK and affects its dynamics in response to DNA double strand breaksResolution of complex ends by Nonhomologous end joining - better to be lucky than good?Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks.Histone 3 lysine 4 methylation during the pre-B to immature B-cell transition.Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme polymerase Mu.Polμ tumor variants decrease the efficiency and accuracy of NHEJ.DNA Ligase IV Guides End-Processing Choice during Nonhomologous End Joining.The fidelity of the ligation step determines how ends are resolved during nonhomologous end joining.Translesion synthesis past platinum DNA adducts by human DNA polymerase mu.Non-homologous end joining requires that the DNA-PK complex undergo an autophosphorylation-dependent rearrangement at DNA ends.DNA repair factor RAD18 and DNA polymerase Polκ confer tolerance of oncogenic DNA replication stress.Regulation of human polλ by ATM-mediated phosphorylation during non-homologous end joining.Everything is E(Z): linking histone methylation to B cell development.Loading of the nonhomologous end joining factor, Ku, on protein-occluded DNA endsHigh-Throughput Analysis of DNA Break-Induced Chromosome Rearrangements by Amplicon SequencingGenetic determinants of cellular addiction to DNA polymerase thetaMechanistic basis for microhomology identification and genome scarring by polymerase thetaRibonucleotide incorporation enables repair of chromosome breaks by nonhomologous end joiningThe Drosophila melanogaster Ortholog of RFWD3 Functions Independently of RAD51 During DNA RepairUnexpected behavior of DNA polymerase Mu opposite template 8-oxo-7,8-dihydro-2'-guanosine
P50
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description
researcher
@en
wetenschapper
@nl
name
Dale A Ramsden
@en
Dale A Ramsden
@nl
type
label
Dale A Ramsden
@en
Dale A Ramsden
@nl
prefLabel
Dale A Ramsden
@en
Dale A Ramsden
@nl
P106
P31
P496
0000-0003-1575-4748