about
Radiochemistry, PET Imaging, and the Internet of Chemical ThingsHigh affinity radiopharmaceuticals based upon lansoprazole for PET imaging of aggregated tau in Alzheimer's disease and progressive supranuclear palsy: synthesis, preclinical evaluation, and lead selectionSynthesis and evaluation of [(11)C]PyrATP-1, a novel radiotracer for PET imaging of glycogen synthase kinase-3β (GSK-3β)Ethanolic carbon-11 chemistry: the introduction of green radiochemistry.Carbon-11 labeled cathepsin K inhibitors: syntheses and preliminary in vivo evaluationRadiosyntheses using fluorine-18: the art and science of late stage fluorinationEvaluation of [(11)C]N-Methyl Lansoprazole as a Radiopharmaceutical for PET Imaging of Tau Neurofibrillary Tangles.Targeting Metal-Aβ Aggregates with Bifunctional Radioligand [(11)C]L2-b and a Fluorine-18 Analogue [(18)F]FL2-bHighlighting the Versatility of the Tracerlab Synthesis Modules. Part 1: Fully Automated Production of [F]Labelled Radiopharmaceuticals using a Tracerlab FX(FN).Synthesis and Initial in Vivo Studies with [(11)C]SB-216763: The First Radiolabeled Brain Penetrative Inhibitor of GSK-3.Synthesis and evaluation of [(11)C]PBD150, a radiolabeled glutaminyl cyclase inhibitor for the potential detection of Alzheimer's disease prior to amyloid β aggregation.Enhanced radiosyntheses of [¹¹C]raclopride and [¹¹C]DASB using ethanolic loop chemistry.[(11)C]Ascorbic and [(11)C]dehydroascorbic acid, an endogenous redox pair for sensing reactive oxygen species using positron emission tomographyNovel fluorine-18 PET radiotracers based on flumazenil for GABAA imaging in the brain.Clinical Applications of Small-molecule PET Radiotracers: Current Progress and Future Outlook.Fluorine-18 patents (2009-2015). Part 1: novel radiotracers.Preclinical Evaluation of 11C-Sarcosine as a Substrate of Proton-Coupled Amino Acid Transporters and First Human Application in Prostate Cancer.An updated synthesis of [11 C]carfentanil for positron emission tomography (PET) imaging of the μ-opioid receptor.Fluorine-18 patents (2009-2015). Part 2: new radiochemistry.Cu-Mediated C-H 18F-Fluorination of Electron-Rich (Hetero)arenesCopper-catalyzed [18F]fluorination of (mesityl)(aryl)iodonium salts.Copper-Mediated Radiofluorination of Arylstannanes with [18F]KF.A fully-automated one-pot synthesis of [18F]fluoromethylcholine with reduced dimethylaminoethanol contamination via [18F]fluoromethyl tosylate.Synthesis of Diverse (11)C-Labeled PET Radiotracers via Direct Incorporation of [(11)C]CO2.In Vivo Metabolic Trapping Radiotracers for Imaging Monoamine Oxidase-A and -B Enzymatic Activity.Development of Customized [18F]Fluoride Elution Techniques for the Enhancement of Copper-Mediated Late-Stage Radiofluorination.Late-stage [(18)F]Fluorination: New Solutions to Old ProblemsIntranasal Opioid Administration in Rhesus Monkeys: PET Imaging and Antinociception.Moving Metal-Mediated (18)F-Fluorination from Concept to Clinic.Synthesis of [18F]Arenes via the Copper-Mediated [18F]Fluorination of Boronic Acids.Synthesis and Evaluation of [(18)F]RAGER: A First Generation Small-Molecule PET Radioligand Targeting the Receptor for Advanced Glycation Endproducts.Identification of [18F]TRACK, a Fluorine-18-Labeled Tropomyosin Receptor Kinase (Trk) Inhibitor for PET Imaging.Automated synthesis of PET radiotracers by copper-mediated 18 F-fluorination of organoborons: Importance of the order of addition and competing protodeborylation.(-)-[(18) F]Flubatine: evaluation in rhesus monkeys and a report of the first fully automated radiosynthesis validated for clinical use.High-Yielding Automated Convergent Synthesis of No-Carrier-Added [11C-Carbonyl]-Labeled Amino Acids Using the Strecker Reaction.Is logP truly dead?Green approaches to late-stage fluorination: radiosyntheses of (18)F-labelled radiopharmaceuticals in ethanol and water.Determination of residual Kryptofix 2.2.2 levels in [18F]-labeled radiopharmaceuticals for human use.Targeted nanoparticles for multimodal imaging of the receptor for advanced glycation end-productsSynthesis and Initial In Vivo Evaluation of [C]AZ683-A Novel PET Radiotracer for Colony Stimulating Factor 1 Receptor (CSF1R)
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P50
description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Peter J H Scott
@en
Peter J H Scott
@nl
type
label
Peter J H Scott
@en
Peter J H Scott
@nl
prefLabel
Peter J H Scott
@en
Peter J H Scott
@nl
P31
P496
0000-0002-6505-0450