Baseline (Week 0) and Week 8
From the start of study treatment until 3 months after the last dose of study treatment
Time to identified response or ...... in Part 1 (approx. 5 months).
post-intervention (8 weeks after baseline)
One month after the administration of the 3rd vaccine dose i.e. Month 5
Post-treatment assessment (10-12 weeks)
at baseline (first appointment)
Prenatal: 20, 28, 36weeks.Postnatal: 4 and 10 weeks
Change from baseline mean dail ...... (end of texting intervention)
Baseline and at 12 months after enrollment
after four treatment courses of Decitabine, after 6 months
Basline, 0, 15, 30, 45, 60, 90, 120, 180, 240
Blood samples will be collecte ...... 1344 and 2016 hours post dose
Single dose period, Day 0 (baseline) and 24 hours post dose Day 1.
Testing is performed at baseline and every six months thereafter.
Day 4 for single-dose cohorts
two times a week until Day 28, ...... ), then 4 wks after treatment.
Measured at time of procedure
Throughout eight weeks of treatment (baseline week 2, 4, 6 and 8)
2 weeks before surgery (pre-operative) and hours after the surgery (post operative)
During the procedure (up to 1 day)
Baseline and Endpoint (Week 24 or last observation after baseline)
Through 6 weeks after surgery
At performing the pregnancy test 11 days post-embryo transfer