The 2000–01 Michigan State Spartans men's basketball team represented Michigan State University in the 2000–01 NCAA Division I men's basketball season. Tom Izzo, in his sixth year as head coach, led the team that played their home games at Breslin Center in East Lansing, Michigan and were members of the Big Ten Conference. The Spartans finished the season with a record of 27–5, 13–3 to finish in a tie for the Big Ten regular season championship for the fourth consecutive year. They received an at-large bid to the NCAA Tournament. For the third consecutive year, they received a No. 1 seed and reached the Final Four before falling to Arizona.