The 2010–11 Liga Nacional de Ascenso de Honduras season is the 32nd season of the Liga Nacional de Ascenso de Honduras, the second division of football in Honduras. It is contested by 28 teams split into two zones with two divisions each. The season is split into two separate competitions, the Apertura and the Clausura. After the end of the Clausura, the winners of both competitions will face off against each other in order to determine the team which will earn promotion to the Liga Nacional de Fútbol de Honduras for the 2011–12 season.