The 2010 Philippine Collegiate Championship was the third tournament of the Philippine Collegiate Championship (PCC) for basketball in its current incarnation, and the eighth edition overall. The champion teams from the University Athletic Association of the Philippines (UAAP), National Collegiate Athletic Association (NCAA), the Cebu Schools Athletic Foundation, Inc. (CESAFI) and 3 other Metro Manila leagues took part in the final tournament dubbed as the "Sweet Sixteen". Other teams had to qualify in the zonal tournaments to round out the 16 teams in the tournament.