Regional League Championships 2010 was contested by the five regional league winners and runners up of the 3rd level championships of Thailand. The two best 3rd placed teams from the regional leagues also take part Twelve teams were split into two groups of A & B, with the top two teams from group A & B gaining promotion to the Thai 1st Division for the 2011 campaign, along with this, the two group winners would play off to determine the overall champions.