The 2010 Stony Brook Seawolves football team represented Stony Brook University in the 2010 college football season as an associate member of the Big South Conference. The team was coached by Chuck Priore and played their home games in Kenneth P. LaValle Stadium at Stony Brook, NY. The Seawolves ended their regular season 6–5, 5–1 in Big South play to earn it second straight Big South conference title shared with Liberty and Coastal Carolina. Due to a three way tie in the conference title the automatic bid to the FCS playoff was given to Coastal Carolina, not Stony Brook who allowed more points against the Big South opponents.