2010 US Open – Men's Singles

Juan Martín del Potro was the defending champion, but chose not to participate this year, after undergoing a wrist operation in May and only starting to practice again in August. Del Potro was the third man in the Open Era not to defend his US Open title, after Ken Rosewall in 1971 (due to conflicts between the World Championship Tennis (WCT) and the International Lawn Tennis Federation (ILTF)), and Pete Sampras in 2003 (who unofficially retired after the 2002 final). For the first time in U.S. Open history, no American player was seeded in the top 8 and thus expected to reach the quarter finals; and this was reflected in the result.

2010 US Open – Men's Singles

Juan Martín del Potro was the defending champion, but chose not to participate this year, after undergoing a wrist operation in May and only starting to practice again in August. Del Potro was the third man in the Open Era not to defend his US Open title, after Ken Rosewall in 1971 (due to conflicts between the World Championship Tennis (WCT) and the International Lawn Tennis Federation (ILTF)), and Pete Sampras in 2003 (who unofficially retired after the 2002 final). For the first time in U.S. Open history, no American player was seeded in the top 8 and thus expected to reach the quarter finals; and this was reflected in the result.