At the Argentine national census of 2010 the total population was 40,117,096, of whom 149,493 (0.37%) identified as Afro-Argentine. The Afro-Argentine population resulting from the slave trade during the centuries of Spanish domination of the Viceroyalty of the Río de la Plata had a major role in Argentine history. Throughout the 18th and 19th centuries they comprised up to fifty percent of the population in some provinces, and had a deep impact on national culture. In the 19th century the Afro-Argentine population declined sharply due to several factors, such as the Argentine War of Independence (c. 1810-1818), high infant mortality rates, low numbers of married couples in this ethnic group, the Paraguayan War, cholera epidemics in 1861 and 1864, and a yellow fever epidemic in 1871. By th