Aralkylamine N-acetyltransferase
Aralkylamine N-acetyltransferase (AANAT) (EC 2.3.1.87), also known as arylalkylamine N-acetyltransferase or serotonin N-acetyltransferase (SNAT), is an enzyme that is involved in the day/night rhythmic production of melatonin, by modification of serotonin. It is in humans encoded by the ~2.5 kb AANAT gene containing four exons, located on chromosome 17q25. The gene is translated into a 23 kDa large enzyme. It is well conserved through evolution and the human form of the protein is 80% identical to sheep and rat AANAT. It is an acetyl-CoA-dependent enzyme of the GCN5-related family of N-acetyltransferases (GNATs). It may contribute to multifactorial genetic diseases such as altered behavior in sleep/wake cycle and research is on-going with the aim of developing drugs that regulate AANAT fun
primaryTopic
Aralkylamine N-acetyltransferase
Aralkylamine N-acetyltransferase (AANAT) (EC 2.3.1.87), also known as arylalkylamine N-acetyltransferase or serotonin N-acetyltransferase (SNAT), is an enzyme that is involved in the day/night rhythmic production of melatonin, by modification of serotonin. It is in humans encoded by the ~2.5 kb AANAT gene containing four exons, located on chromosome 17q25. The gene is translated into a 23 kDa large enzyme. It is well conserved through evolution and the human form of the protein is 80% identical to sheep and rat AANAT. It is an acetyl-CoA-dependent enzyme of the GCN5-related family of N-acetyltransferases (GNATs). It may contribute to multifactorial genetic diseases such as altered behavior in sleep/wake cycle and research is on-going with the aim of developing drugs that regulate AANAT fun
has abstract
Aralkylamine N-acetyltransfera ...... that regulate AANAT function.
@en
CH3CO-S-CoA + Serotonin HS-CoA ...... erden als Substrat akzeptiert.
@de
La aralchilammina N-acetiltran ...... ansferasi (numero EC 2.3.1.5).
@it
La sérotonine N-acétyltransfér ...... ogie cellulaire et moléculaire
@fr
Serotonina N-acetiltransferasa ...... ficada por el gen HGNC AANAT .
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Арилалкиламин-N-ацетилтрансфер ...... ует синтез гормона мелатонина.
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738,781,534
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Crystallographic structure of aralkylamine N-acetyltransferase.
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Aralkylamine N-acetyltransfera ...... drugs that regulate AANAT fun
@en
CH3CO-S-CoA + Serotonin HS-CoA ...... erden als Substrat akzeptiert.
@de
La aralchilammina N-acetiltran ...... ansferasi (numero EC 2.3.1.5).
@it
La sérotonine N-acétyltransfér ...... ogie cellulaire et moléculaire
@fr
Serotonina N-acetiltransferasa ...... ficada por el gen HGNC AANAT .
@es
Арилалкиламин-N-ацетилтрансфер ...... ует синтез гормона мелатонина.
@ru
label
Aralchilammina N-acetiltransferasi
@it
Aralkylamine N-acetyltransferase
@en
Serotonin-N-Acetyltransferase
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Serotonina N-acetiltransferasa
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Sérotonine N-acétyltransférase
@fr
Арилалкиламин-N-ацетилтрансфераза
@ru
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Aralkylamine N-acetyltransferase
@en