"Baby, You Knock Me Out" is the fifth episode of the ninth season of the animated comedy series Family Guy. It originally aired on Fox in the United States on November 14, 2010. The episode follows housewife Lois after she is convinced to become a championship boxer. As she continues fighting, however, she eventually decides to go into retirement, only to be challenged by the top ranked fighter in all of Rhode Island. Deciding to accept the challenge, Lois faces the fight of her life, causing her to unleash pent-up anger at Peter.