Berryville Historic District is a national historic district located at Berryville, Clarke County, Virginia. It encompasses 313 contributing buildings and 1 contributing object in the town of Berryville. They include a variety of residential, commercial, and industrial buildings dating from the late 18th century to the 1930s. Notable buildings include the Treadwell Smith House (Hawthorne Hall) (c. 1820), Sarah Stribling House (Battletown Inn) (c. 1810), Crow's Nest (1830s), Berryville Presbyterian Church (c. 1854), Grace Episcopal Church (1857), Coiner's Department Store (c. 1896), Clarke Milling Company (nowCustom Millwork, Inc.), H. W. Baker Grain Warehouse (now Berryville Farm Supply), H. B. Whiting Brothers Warehouse, Berryville railroad depot (1910), the First National Bank (c. 1910),