The Big Bend region of Florida, U.S.A., is an informal region of the state with no official surveyed boundary. It generally includes the counties of the Florida Panhandle east of the Apalachicola River. The Big Bend Coast is the marshy coast without barrier islands that extends along the Gulf of Mexico coast of Florida from the Ocklockonee River to Anclote Key. Private agencies that self-identify as serving the Big Bend region often include Franklin, Gadsden, Jefferson, Leon, Liberty, Madison, Taylor and Wakulla counties in their service areas. The principal city in the region is Tallahassee.