Buffalo Presbyterian Church and Cemeteries is a historic Presbyterian church and cemeteries located at 1333 Carthage Street in Sanford, Lee County, North Carolina. It was built in 1879, and is a two-story, gable-fronted, Gothic Revival style frame building. The front facade features lancet-arched double-leaf entries, lancet-arched windows, and a three-stage projecting entry tower with a flared, pyramidal roof and finial. Associated with the church is the manse built in 1926. It is a two-story, hip-roofed frame dwelling with Colonial Revival detailing. Also on the property are the original church cemetery, a cemetery for African-American congregants, the Matthews family plot, and the main cemetery. It is the oldest Presbyterian Church in Lee County, Sanford, North Carolina. This is an activ