Clem's Opera House, at Main and Post Sts. in Gresham, Nebraska, is a building constructed in about 1891. It has also been denoted NeHBS #YK04-1 and OHBIN #03-01-02. The opera house served as a venue for both touring and home-grown theatrical and musical performances, for lectures, and for movies. It also provided a location for community gatherings, including box socials, high-school commencements, farmer's institutes, and political-party meetings. The building was listed on the National Register of Historic Places in 1988.