David Holmes (16 November 1843 – 14 January 1906) was a British trade unionist. Born in Manchester, Holmes worked as a weaver from the age of eight. When he was ten, he ran away from home to live with an uncle in Padiham. He continued weaving, but also received some education at the local Unitarian chapel. Holmes was a member of the Parliamentary Committee of the Trades Union Congress (TUC), where he opposed the new unions which organised unskilled labour, and attended various international conferences representing the organisation.