DePaul Cristo Rey High School (DPCR) is a private, college-preparatory high school located in the Clifton neighborhood of Cincinnati, Ohio, United States. The non-diocesan school, which opened June 5, 2011, is one of 23 Catholic high schools that serve the Archdiocese of Cincinnati. Named after St. Vincent de Paul, it is operated by the Sisters of Charity of Cincinnati as the 25th member of the Cristo Rey Network of work-study schools that target students from low-income families.