Denham Lock Wood is a 6.3 hectare biological Site of Special Scientific Interest (SSSI) next to the Grand Union Canal, and near Denham in the London Borough of Hillingdon. It was notified in 1986 and is managed by the London Wildlife Trust on behalf of Hillingdon Council. It lies within the Colne Valley Regional Park. Access is by a footbridge across Frays River from Frays Farm Meadows, which is also an SSSI managed by the London Wildlife Trust, south of the Wood. Access to the Meadows is by a stile on the east side of the Grand Union Canal at Denham Lock.