The Deposition of Christ is a painting by the Italian artist Agnolo di Cosimo, known as Bronzino, executed in 1540–45. It is housed in the Musée des Beaux-Arts de Besançon, France. The work is signed OPERA DEL BRONZINO FIORENTINO. It was originally commissioned for the chapel of Eleonora of Toledo in Palazzo Vecchio, Florence. Her husband, Grand Duke Cosimo I de' Medici, however, presented the picture to the French Cardinal Nicolas Perrenot de Granvelle, chancellor of Emperor Charles V, as a political move. At Granvelle's death (1551), the work was placed in his funerary chapel at his hometown of Besançon. Originally, there were two side panels: the left one, depicting St. John the Baptist, is now in J. Paul Getty Museum; the right one, depicting Saint Cosmas, no longer exists.